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Complement System and Fc Receptors: Genetics

  1. Anja Roos,
  2. Leendert A Trouw,
  3. Andreea Ioan-Facsinay,
  4. Mohamed R Daha,
  5. J Sjef Verbeek

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005992

eLS

eLS

How to Cite

Roos, A., Trouw, L. A., Ioan-Facsinay, A., Daha, M. R. and Verbeek, J. S. 2006. Complement System and Fc Receptors: Genetics. eLS. .

Author Information

  1. Leiden University Medical Centre, Leiden, The Netherlands

Publication History

  1. Published Online: 27 JAN 2006

Abstract

The complement system is a key component of the innate immune system that is involved in eliminating unwanted self and nonself material via cellular and humoral mechanisms. Complement receptors and Fc receptors, expressed on effector cells, have a synergistic role in antibody-mediated immune modulation and antigen clearance.

Keywords:

  • complement;
  • Fc receptors;
  • innate immunity;
  • phagocytosis;
  • antibodies