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Tumor Suppressor Genes

  1. Martin L Hooper

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006005

eLS

eLS

How to Cite

Hooper, M. L. 2006. Tumor Suppressor Genes. eLS. .

Author Information

  1. University of Edinburgh, Edinburgh, UK

Publication History

  1. Published Online: 27 JAN 2006

Abstract

When functioning normally, a tumor suppressor gene prevents the formation of one or more types of cancer. Mutations in tumor suppressor genes that interfere with their function can be inherited in the germ line or can occur in somatic cells; the accumulation of such mutations can allow cancer to develop.

Keywords:

  • disease;
  • tumor;
  • cancer;
  • carcinogenesis;
  • cancer genetics