Nuclear Receptors and Disease
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Love, J. D. 2006. Nuclear Receptors and Disease. eLS.
- Published Online: 27 JAN 2006
Nuclear receptors are ligand-modulated transcription factors that act in the nucleus to regulate target gene transcription through interaction with cofactor proteins. Owing to their roles in many diverse cellular processes, nuclear receptors are important therapeutic targets and aberrant receptor action results in significant human disease.
- transcription factors;