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Allele Spectrum of Human Genetic Disease

  1. Kenneth M Weiss

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006033

eLS

eLS

How to Cite

Weiss, K. M. 2006. Allele Spectrum of Human Genetic Disease. eLS. .

Author Information

  1. Pennsylvania State University, University Park, Pennsylvania, USA

Publication History

  1. Published Online: 27 JAN 2006

This is not the most recent version of the article. View current version (15 MAY 2017)

Abstract

The distribution of genetic variation associated with a specified phenotype is sometimes known as its genetic architecture or allele frequency ‘spectrum’. These terms may refer to a disease phenotype or to variation in the trait in the general population.

Keywords:

  • genetic architecture;
  • allele frequencies;
  • allele spectrum;
  • genotype–phenotype relationships;
  • genetic variation