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Blood Groups: Molecular Genetic Basis

  1. Neil D Avent

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006034

eLS

eLS

How to Cite

Avent, N. D. 2006. Blood Groups: Molecular Genetic Basis. eLS. .

Author Information

  1. University of the West of England, Bristol, UK

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Human blood groups are of clinical significance in transfusion medicine and blood group incompatible pregnancy. Blood groups are due to polymorphic structures on human red cells, may arise from carbohydrates or proteins and include most species of proteins found in red cell membranes including transporters, adhesion molecules, structural proteins, complement control proteins, receptors and membrane-bound enzymes.

Keywords:

  • blood group polymorphisms;
  • single nucleotide polymorphisms;
  • genotyping;
  • red cell membrane;
  • blood groups;
  • molecular basis;
  • erythrocyte membrane