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Mismatch Repair Genes

  1. Päivi Peltomäki,
  2. Minna Nyström-Lahti

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006045

eLS

eLS

How to Cite

Peltomäki, P. and Nyström-Lahti, M. 2006. Mismatch Repair Genes. eLS. .

Author Information

  1. University of Helsinki, Helsinki, Finland

Publication History

  1. Published Online: 27 JAN 2006

Abstract

The mismatch repair (MMR) system is necessary for the maintenance of genomic stability. The primary role of MMR is to correct errors such as base/base mismatches and small insertions/deletions that arise during DNA synthesis and recombination.

Keywords:

  • DNA mismatch repair;
  • hereditary nonpolyposis colon cancer;
  • microsatellite instability;
  • MutL;
  • MutS