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Melanoma: Genetics

  1. Pamela M Pollock

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006064

eLS

eLS

How to Cite

Pollock, P. M. 2006. Melanoma: Genetics. eLS. .

Author Information

  1. National Institutes of Health, Bethesda, Maryland, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Melanoma is an aggressive skin cancer. Germ-line mutations in CDKN2A and CDK4 are found in about 20% of melanoma families. Mutations in a variety of genes have been reported in sporadic melanomas.

Keywords:

  • melanoma;
  • CDKN2A;
  • CDK4;
  • mutation;
  • senescence