Chromosomal Instability (CIN) in Cancer
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Schmutte, C. 2006. Chromosomal Instability (CIN) in Cancer. eLS. .
- Published Online: 27 JAN 2006
Chromosomal instability is definied as an increased rate of gross chromosomal abnormalities combined with loss of heterozygosity and change in ploidy of genes structural CIN, and the inability of cells to maintain a diploid karyotype numerical CIN.
- chromosome instability;
- Darwinian evolution, microsatelite instability