Multidrug Resistance in Cancer: Genetics of ABC Transporters
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Ishikawa, T. 2006. Multidrug Resistance in Cancer: Genetics of ABC Transporters. eLS. .
- Published Online: 27 JAN 2006
Multidrug resistance in human cancer is the major obstacle to long-term, sustained response of a patient to chemotherapy. It has been convincingly documented that several adenosine triphosphate-binding cassette transporters cause multidrug resistance in cancer cells by actively extruding the clinically administered chemotherapeutic drugs.
- drug response;
- ABC transporter;