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Mutation Rate: Sex Biases

  1. Laurence D Hurst

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006093



How to Cite

Hurst, L. D. 2006. Mutation Rate: Sex Biases. eLS. .

Author Information

  1. University of Bath, Bath, UK

Publication History

  1. Published Online: 27 JAN 2006


At least in humans, more spontaneous point mutations occur in the male germ line than in the female germ line. One explanation for this is the greater number of germ-cell divisions in males than in females.


  • point mutations;
  • germ-cell divisions;
  • sex chromosomes;
  • methylation;
  • neutral evolution;
  • dominance