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DNA Replication Fidelity

  1. Errol C Friedberg,
  2. Paula L Fischhaber

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006172

eLS

eLS

How to Cite

Friedberg, E. C. and Fischhaber, P. L. 2006. DNA Replication Fidelity. eLS. .

Author Information

  1. UT Southwestern Medical Center, Dallas, Texas, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

DNA polymerases are proteins that catalyse the polymerization of DNA. Fidelity in this process refers to the ability of the polymerase to avoid or to correct errors in the newly synthesized DNA strand.

Keywords:

  • DNA polymerase;
  • DNA replication;
  • replicational fidelity;
  • Y family polymerases;
  • xeroderma pigmentosum;
  • mutation