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Transcriptomics and Proteomics: Integration?

  1. Bent Honoré,
  2. Morten Østergaard

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0006188

eLS

eLS

How to Cite

Honoré, B. and Østergaard, M. 2006. Transcriptomics and Proteomics: Integration?. eLS. .

Author Information

  1. University of Aarhus, Aarhus, Denmark

Publication History

  1. Published Online: 27 JAN 2006

Abstract

The genes are transcribed to pre-messenger RNA, further processed to messenger RNA (transcripts), and finally translated into protein. The transcriptome constitutes the complete set of different transcripts that is synthesized in the lifetime of a cell or a tissue. The proteome refers to the complete set of proteins that is expressed, and modified following expression in the lifetime of a cell or a given tissue. Transcriptomics refers to the study of the transcriptome, while proteomics refers to the study of the proteome using large-scale technologies for transcript or protein analyses. The two disciplines each provide unique information and supplement each other.

Keywords:

  • transcriptome;
  • transcriptomics;
  • proteome;
  • proteomics