• 1
    Masoro, EJ. (1996) Possible mechanisms underlying the antiaging actions of caloric restriction. Toxicol Pathol. 24: 738741.
  • 2
    Stevenson, J. A. F., Feleki, V., Szlavko, A., Beaton, J.R. (1964) Food restriction and lipogenesis in the rat. Proc Soc Exp Biol Med. 116: 178182.
  • 3
    Weindruch, R. (1999) Animal models. In Masoro, EJ (ed). Handbook of Physiology. Oxford University Press: New York. 3752.
  • 4
    Weindruch, R., Walford, R. L., Fligiel, S., Guthrie, D. (1986) The retardation of aging in mice by dietary restriction: longevity, cancer, immunity, and lifetime energy intake. J Nutr. 116: 641654.
  • 5
    DiGirolamo, M., Smith, J. E., Esposito, J., Trehern, MS. (1973) Effects of diet on body growth, adipose tissue cellularity and spontaneous activity in the growing rat. Fed Proc. 32: 940. (abstr).
  • 6
    Hill, J. O., Latiff, A., DiGirolamo, M. (1985) Effects of variable caloric restriction on utilization of ingested energy in rats. Am J Physiol. 248: R549R559.
  • 7
    Barzilai, N., Wang, J., Massilon, D., Vuguin, P., Hawkins, M., Rossetti, L. (1997) Leptin selectively decreases visceral adiposity and enhances insulin action. J Clin Invest. 100: 31053110.
  • 8
    Duffy, P. H., Feuers, R. J., Leakey, J. A., Nakamura, K., Turturro, A., Hart, RW. (1989) Effect of chronic caloric restriction on physiological variables related to energy metabolism in the male Fischer 344 rat. Mech Ageing Dev. 48: 117133.
  • 9
    Duffy, P. H., Leakey, J. E., Pipkin, J. L., Turturro, A., Hart, RW. (1997) The physiologic, neurologic, and behavioral effects of caloric restriction related to aging, disease, and environmental factors. Environ Res. 73: 242248.
  • 10
    DiGirolamo, M., Ander, B. L., Francendese, AA. (1981) Development and testing of an automated food dispenser for small rodents. Lab Anim Sci. 31: 476481.
  • 11
    DiGirolamo, M., Francendese, A. A., Crandall, D., Fried, SK. (1982) Effects of age and chronic food restriction (CFR) on rat body composition and adipose tissue cellularity. Federation Proc. 41: 1674
  • 12
    DiGirolamo, M., Fine, J. B., Tagra, K., Rossmanith, R. (1998) Qualitative regional differences in adipose tissue growth and cellularity in male Wistar rats fed ad libitum. Am J Physiol. 274: R1460R1467.
  • 13
    Hirsch, J., Gallian, E. (1968) Methods for the determination of adipose cell size in man and animals. J Lipid Res. 9: 110119.
  • 14
    Folch, J., Lees, M., Sloane-Stanley, GH. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1956: 497508.
  • 15
    Etherton, T. D., Wangsness, P. J., Hammers, V. M., Ziegler, JH. (1982) Effect of dietary restriction on carcass composition and adipocyte cellularity of swine with different propensities for obesity. J Nutr. 112: 23142323.
  • 16
    Raymond, J. L., Schipke, C. A., Becker, J. M., Lloyd, R. D., Moody, FG. (1986) Changes in body composition and dietary intake after gastric partitioning for morbid obesity. Surgery. 99: 1519.
  • 17
    Bailey, J. W., Anderson, D. B., Anderson, M. W., Verstegen, A., Curtis, SE. (1980) Relative growth rates of various fat depots in Sprague Dawley rats. Growth. 44: 220229.
  • 18
    Mrosovsky, N. (1986) Body fat: what is regulated? Physiol Behav. 38: 407414.
  • 19
    Fine, J. B., Bai, Y., Cutchins, A. G., Porter, M. H., DiGirolamo, M. Graded caloric restriction, circulating leptin levels, and regional adipose leptin gene expression in male and female rats (submitted for publication).
  • 20
    Fine, J. B., Villafuerte, B. C., Bai, Y. (1998) Effects of chronic food restriction on circulating levels and adipose regional gene expression of leptin and IGF-1. Int J Obes. 22(Suppl 3): S164
  • 21
    Masoro, EJ. (1998) Influence of caloric intake on aging and on the response to stressors. J Toxicol Environ Health B Crit Rev. 1: 243257.