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Exercise-Induced Reduction in Obesity and Insulin Resistance in Women: a Randomized Controlled Trial
Article first published online: 6 SEP 2012
2004 North American Association for the Study of Obesity (NAASO)
Volume 12, Issue 5, pages 789–798, May 2004
How to Cite
Ross, R., Janssen, I., Dawson, J., Kungl, A.-M., Kuk, J. L., Wong, S. L., Nguyen-Duy, T.-B., Lee, S., Kilpatrick, K. and Hudson, R. (2004), Exercise-Induced Reduction in Obesity and Insulin Resistance in Women: a Randomized Controlled Trial. Obesity Research, 12: 789–798. doi: 10.1038/oby.2004.95
- Issue published online: 6 SEP 2012
- Article first published online: 6 SEP 2012
- Received for review September 11, 2003; Accepted in final form March 15, 2004
- weight loss;
- visceral fat;
- abdominal fat;
- insulin resistance
Objectives: To determine the effects of equivalent diet- or exercise-induced weight loss and exercise without weight loss on subcutaneous fat, visceral fat, and insulin sensitivity in obese women.
Research Methods and Procedures: Fifty-four premenopausal women with abdominal obesity [waist circumference 110.1 ± 5.8 cm (mean ± SD)] (BMI 31.3 ± 2.0 kg/m2) were randomly assigned to one of four groups: diet weight loss (n = 15), exercise weight loss (n = 17), exercise without weight loss (n = 12), and a weight-stable control group (n = 10). All groups underwent a 14-week intervention.
Results: Body weight decreased by ∼6.5% within both weight loss groups and was unchanged in the exercise without weight loss and control groups. In comparison with controls, cardiorespiratory fitness improved within the exercise groups only (p < 0.01). Reduction in total, abdominal, and abdominal subcutaneous fat within the exercise weight loss group was greater (p < 0.001) than within all other groups. The reduction in total and abdominal fat within the diet weight loss and exercise without weight loss groups was greater than within controls (p < 0.001) but not different from each other (p > 0.05). Visceral fat decreased within all treatment groups (p < 0.008), and these changes were not different from each other. In comparison with the control group, insulin sensitivity improved within the exercise weight loss group alone (p < 0.001).
Discussion: Daily exercise without caloric restriction was associated with substantial reductions in total fat, abdominal fat, visceral fat, and insulin resistance in women. Exercise without weight loss was also associated with a substantial reduction in total and abdominal obesity.