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Keywords:

  • insulin resistance;
  • fatty acids;
  • glycogen;
  • glucose transport;
  • magnetic resonance spectroscopy

Abstract

Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much effort, the underlying factors that are responsible for it are poorly understood. In this review, we focus on some recent advances in our understanding of the pathogenesis of insulin resistance in humans that have been made using magnetic resonance spectroscopy.