The Effects of a Low-Carbohydrate Ketogenic Diet and a Low-Fat Diet on Mood, Hunger, and Other Self-Reported Symptoms
Version of Record online: 6 SEP 2012
2007 North American Association for the Study of Obesity (NAASO)
Volume 15, Issue 1, page 182, January 2007
How to Cite
McClernon, F. J., Yancy, W. S., Eberstein, J. A., Atkins, R. C. and Westman, E. C. (2007), The Effects of a Low-Carbohydrate Ketogenic Diet and a Low-Fat Diet on Mood, Hunger, and Other Self-Reported Symptoms. Obesity, 15: 182. doi: 10.1038/oby.2007.516
- Issue online: 6 SEP 2012
- Version of Record online: 6 SEP 2012
- Received for review December 19, 2005, Accepted in final from September 12, 2006
- low-carbohydrate diet;
Objective: To investigate the effects of weight loss diets on mood, food cravings, and other self-reported symptoms.
Research Methods and Procedures: Mood and other symptoms were evaluated by participant self-report using the Atkins Health Indicator Test (AHIT) in individuals undergoing weight loss following either a low-carbohydrate, ketogenic diet (LCKD) or a low-fat diet (LFD). Participants were 119 overweight community volunteers randomized to an LCKD or an LFD. An additional 51 participants who had completed an earlier trial contributed data for the psychometric analyses but were not included in the prospective analyses. Self-reported symptom levels on seven scales factor-analytically derived from the AHIT (negative affect, fatigue, somatic symptoms, physical effects of hunger, insomnia, hunger, and stomach problems) were acquired during 12 visits.
Results: After adjusting for the change in BMI over the course of the trial, participants experienced significant improvements in most symptoms regardless of diet. Diet group × visit interactions were observed for negative affect [F(9,803) = 2.30, p = 0.015] and hunger [F(9,803) = 3.62, p < 0.0002]. Examination of means indicated that the LCKD group reported less negative affect and hunger, compared with the LFD group.
Discussion: Regardless of diet, participants experienced significant improvement in a broad range of symptoms. Symptoms of negative affect and hunger improved to a greater degree in patients following an LCKD compared with those following an LFD. Whether these symptom changes explain the greater short-term weight loss generally experienced by LCKD followers deserves further research.