• 1
    Greenberg AS, Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am J Clin Nutr 2006; 83: 461S465S.
  • 2
    Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000; 21: 697738.
  • 3
    Kelley DE, Thaete FL, Troost F, Huwe T, Goodpaster BH. Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol Endocrinol Metab 2000; 278: E941E948.
  • 4
    Smith SR, Lovejoy JC, Greenway F et al. Contributions of total body fat, abdominal subcutaneous adipose tissue compartments, and visceral adipose tissue to the metabolic complications of obesity. Metab Clin Exp 2001; 50: 425435.
  • 5
    Cancello R, Clément K. Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. BJOG 2006; 113: 11411147.
  • 6
    Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004; 89: 25482556.
  • 7
    Sjöström M, Wold S, Söderström B. PLS discriminant plots. In: Geselma ES, Kanal LN (eds). Pattern Recognition in Practice II. Elsevier: Amsterdam, 1986, pp 461470.
  • 8
    Wold S, Eriksson L, Sjöström M. Partial least squares to latent structures (PLS) in chemistry. In: Schleyer PvR, Allinger NL, Clark T et al. (eds). Encyclopedia of Computational Chemistry. Wiley & Sons: Chicester, 1999, pp 20062022.
  • 9
    Goedecke JH, Wake DJ, Levitt NS et al. Glucocorticoid metabolism within superficial subcutaneous rather than visceral adipose tissue is associated with features of the metabolic syndrome in South African women. Clin Endocrinol (Oxf) 2006; 65: 8187.
  • 10
    Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499502.
  • 11
    El Kenz H, Bergmann P. Evaluation of immunochemiluminometric assays for the measurement of insulin and C-peptide using the ADVIA Centaur. Clin Lab 2004; 50: 171174.
  • 12
    Wallace TM, Levy JC, Matthews DR. Use and abuse of HOMA modeling. Diabetes Care 2004; 27: 14871495.
  • 13
    Gasperoni C, Salgarello M. Rationale of subdermal superficial liposuction related to the anatomy of subcutaneous fat and the superficial fascial system. Aesthetic Plast Surg 1995; 19: 1320.
  • 14
    Johnson D, Dixon AK, Abrahams PH. The abdominal subcutaneous tissue: computed tomographic, magnetic resonance, and anatomical observations. Clin Anat 1996; 9: 1924.
  • 15
    Markman B, Barton FE Jr. Anatomy of the subcutaneous tissue of the trunk and lower extremity. Plast Reconstr Surg 1987; 80: 248254.
  • 16
    Wold S, Sjöström M, Eriksson L. PLS-Regression: a basic tool of chemometrics. Chemometr Intell Lab Syst 2001; 58: 109130.
  • 17
    Cao YL, Hu CZ, Meng X, Wang DF, Zhang J. Expression of TNF-α protein in omental and subcutaneous adipose tissue in obesity. Diabetes Res Clin Pract 2008; 79: 214219.
  • 18
    Poulain-Godefroy O, Lecoeur C, Pattou F, Frühbeck G, Froguel P. Inflammation is associated with a decrease of lipogenic factors in omental fat in women. Am J Physiol Regul Integr Comp Physiol 2008; 295: R1R7.
  • 19
    Fain JN, Madan AK, Hiler ML, Cheema P, Bahouth SW. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology 2004; 145: 22732282.
  • 20
    Huber J, Kiefer FW, Zeyda M et al. CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity. J Clin Endocrinol Metab 2008; 93: 32153221.
  • 21
    Weisberg SP, Hunter D, Huber R et al. CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 2006; 116: 115124.
  • 22
    Skurk T, Herder C, Kräft I et al. Production and release of macrophage migration inhibitory factor from human adipocytes. Endocrinology 2005; 146: 10061011.
  • 23
    Ruan H, Zarnowski MJ, Cushman SW, Lodish HF. Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J Biol Chem 2003; 278: 4758547593.
  • 24
    Verschuren L, Kooistra T, Bernhagen J et al. MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circ Res 2009; 105: 99107.
  • 25
    Cao YL, Wang YX, Wang DF, Meng X, Zhang J. Correlation between omental TNF-α protein and plasma PAI-1 in obesity subjects. Int J Cardiol 2008; 128: 399405.
  • 26
    Zha JM, Di WJ, Zhu T et al. Comparison of gene transcription between subcutaneous and visceral adipose tissue in Chinese adults. Endocr J 2009; 56: 935944.
  • 27
    Walker GE, Verti B, Marzullo P et al. Deep subcutaneous adipose tissue: a distinct abdominal adipose depot. Obesity (Silver Spring) 2007; 15: 19331943.
  • 28
    Lovejoy JC, de la Bretonne JA, Klemperer M, Tulley R. Abdominal fat distribution and metabolic risk factors: effects of race. Metab Clin Exp 1996; 45: 11191124.
  • 29
    van der Merwe MT, Crowther NJ, Schlaphoff GP et al. Evidence for insulin resistance in black women from South Africa. Int J Obes Relat Metab Disord 2000; 24: 13401346.
  • 30
    Goedecke JH, Levitt NS, Lambert EV et al. Differential effects of abdominal adipose tissue distribution on insulin sensitivity in black and white South African women. Obesity (Silver Spring) 2009; 17: 15061512.
  • 31
    Pérez-Enciso M, Tenenhaus M. Prediction of clinical outcome with microarray data: a partial least squares discriminant analysis (PLS-DA) approach. Hum Genet 2003; 112: 581592.
  • 32
    Nguyen DV, Rocke DM. Tumor classification by partial least squares using microarray gene expression data. Bioinformatics 2002; 18: 3950.
  • 33
    Harman-Boehm I, Blüher M, Redel H et al. Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity. J Clin Endocrinol Metab 2007; 92: 22402247.
  • 34
    Weisberg SP, McCann D, Desai M et al. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003; 112: 17961808.
  • 35
    Westerbacka J, Cornér A, Kolak M et al. Insulin regulation of MCP-1 in human adipose tissue of obese and lean women. Am J Physiol Endocrinol Metab 2008; 294: E841E845.
  • 36
    Skopková M, Penesová A, Sell H et al. Protein array reveals differentially expressed proteins in subcutaneous adipose tissue in obesity. Obesity (Silver Spring) 2007; 15: 23962406.