• 1
    Pflieger KL, Treiber FA, Davis H et al. The effect of adiposity on children's left ventricular mass and geometry and haemodynamic responses to stress. Int J Obes Relat Metab Disord 1994;18:117122.
  • 2
    Di Bonito P, Capaldo B, Forziato C et al. Central adiposity and left ventricular mass in obese children. Nutr Metab Cardiovasc Dis 2008;18:613617.
  • 3
    Shah AS, Khoury PR, Dolan LM et al. The effects of obesity and type 2 diabetes mellitus on cardiac structure and function in adolescents and young adults. Diabetologia 2011;54:722730.
  • 4
    Di Salvo G, Pacileo G, Del Giudice EM et al. Abnormal myocardial deformation properties in obese, non-hypertensive children: an ambulatory blood pressure monitoring, standard echocardiographic, and strain rate imaging study. Eur Heart J 2006;27:26892695.
  • 5
    Mehta SK, Holliday C, Hayduk L et al. Comparison of myocardial function in children with body mass indexes >/=25 versus those <25 kg/m2. Am J Cardiol 2004;93:15671569.
  • 6
    Sharpe JA, Naylor LH, Jones TW et al. Impact of obesity on diastolic function in subjects < or = 16 years of age. Am J Cardiol 2006;98:691693.
  • 7
    Rowland T, Bhargava R, Parslow D, Heptulla RA. Cardiac response to progressive cycle exercise in moderately obese adolescent females. J Adolesc Health 2003;32:422427.
  • 8
    Schuster I, Karpoff L, Perez-Martin A et al. Cardiac function during exercise in obese prepubertal boys: effect of degree of obesity. Obesity (Silver Spring) 2009;17:18781883.
  • 9
    Di Bello V, Santini F, Di Cori A et al. Relationship between preclinical abnormalities of global and regional left ventricular function and insulin resistance in severe obesity: a Color Doppler Imaging Study. Int J Obes (Lond) 2006;30:948956.
  • 10
    Tumuklu MM, Etikan I, Kisacik B, Kayikcioglu M. Effect of obesity on left ventricular structure and myocardial systolic function: assessment by tissue Doppler imaging and strain/strain rate imaging. Echocardiography 2007;24:802809.
  • 11
    Kosmala W, Wong C, Kuliczkowska J et al. Use of body weight and insulin resistance to select obese patients for echocardiographic assessment of subclinical left ventricular dysfunction. Am J Cardiol 2008;101:13341340.
  • 12
    Orhan AL, Uslu N, Dayi SU et al. Effects of isolated obesity on left and right ventricular function: a tissue Doppler and strain rate imaging study. Echocardiography 2010;27:236243.
  • 13
    Leggio M, Cruciani G, Sgorbini L et al. Obesity-related adjunctive systo-diastolic ventricular dysfunction in patients with hypertension: echocardiographic assessment with tissue Doppler velocity and strain imaging. Hypertens Res 2011;34:468473.
  • 14
    Ingul C, Tjonna A, Stolen T, Stoylen A, Wisloff U. Impaired cardiac function among obese adolescents. Arch Pediatr Adolesce Med 2010;164:852859.
  • 15
    Dandel M, Lehmkuhl H, Knosalla C, Suramelashvili N, Hetzer R. Strain and strain rate imaging by echocardiography — basic concepts and clinical applicability. Curr Cardiol Rev 2009;5:133148.
  • 16
    Götte MJ, Germans T, Rüssel IK et al. Myocardial strain and torsion quantified by cardiovascular magnetic resonance tissue tagging: studies in normal and impaired left ventricular function. J Am Coll Cardiol 2006;48:20022011.
  • 17
    Sengupta PP, Korinek J, Belohlavek M et al. Left ventricular structure and function: basic science for cardiac imaging. J Am Coll Cardiol 2006;48:19882001.
  • 18
    Shaw SM, Fox DJ, Williams SG. The development of left ventricular torsion and its clinical relevance. Int J Cardiol 2008;130:319325.
  • 19
    Deng Y, Alharthi MS, Thota VR et al. Evaluation of left ventricular rotation in obese subjects by velocity vector imaging. Eur J Echocardiogr 2010;11:424428.
  • 20
    Saltijeral A, Isla LP, Pérez-Rodríguez O et al. Early myocardial deformation changes associated to isolated obesity: a study based on 3D-wall motion tracking analysis. Obesity (Silver Spring) 2011;19:22682273.
  • 21
    Rolland-Cachera MF, Cole TJ, Sempé M et al. Body Mass Index variations: centiles from birth to 87 years. Eur J Clin Nutr 1991;45:1321.
  • 22
    Obert P, Nottin S, Baquet G et al. Two months of endurance training does not alter diastolic function evaluated by TDI in 9–11-year-old boys and girls. Br J Sports Med 2009;43:132135.
  • 23
    de Simone G, Daniels SR, Devereux RB et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight. J Am Coll Cardiol 1992;20:12511260.
  • 24
    Di Bella G, Zito C, Gaeta M et al. Semiautomatic quantification of left ventricular function by two-dimensional feature tracking imaging echocardiography. A comparison study with cardiac magnetic resonance imaging. Echocardiography 2010;27:791797.
  • 25
    Nagueh SF, Middleton KJ, Kopelen HA, Zoghbi WA, Quiñones MA. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol 1997;30:15271533.
  • 26
    Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest 1975;56:5664.
  • 27
    Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978;58:10721083.
  • 28
    Pirat B, Khoury DS, Hartley CJ et al. A novel feature-tracking echocardiographic method for the quantitation of regional myocardial function: validation in an animal model of ischemia-reperfusion. J Am Coll Cardiol 2008;51:651659.
  • 29
    Bussadori C, Moreo A, Di Donato M et al. A new 2D-based method for myocardial velocity strain and strain rate quantification in a normal adult and paediatric population: assessment of reference values. Cardiovasc Ultrasound 2009;13:78.
  • 30
    Alharthi MS, Jiamsripong P, Calleja A et al. Selective echocardiographic analysis of epicardial and endocardial left ventricular rotational mechanics in an animal model of pericardial adhesions. Eur J Echocardiogr 2009;10:357362.
  • 31
    Tayyareci Y, Yildirimturk O, Yurdakul S, Aytekin S. Clinical implications of velocity vector imaging-based two dimensional strain imaging for the evaluation of left ventricular systolic functions. Minerva Cardioangiol 2010;58:399407.
  • 32
    Butz T, Lang CN, Van Bracht M et al. Segment-orientated analysis of two-dimensional strain and strain rate as assessed by velocity vector imaging in patients with acute myocardial infarction. Int J Med Sci 2011;8:106113.
  • 33
    Van Dalen BM, Vletter WB, Soliman OI, ten Cate FJ, Geleijnse ML. Importance of transducer position in the assessment of apical rotation by speckle tracking echocardiography. J Am Soc Echocardiogr 2008;21:895898.
  • 34
    Doucende G, Schuster I, Rupp T et al. Kinetics of left ventricular strains and torsion during incremental exercise in healthy subjects: the key role of torsional mechanics for systolic-diastolic coupling. Circ Cardiovasc Imaging 2010;3:586594.
  • 35
    Matthews DR, Hosker JP, Rudenski AS et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412419.
  • 36
    Burns AT, La Gerche A, D'hooge J, MacIsaac AI, Prior DL. Left ventricular strain and strain rate: characterization of the effect of load in human subjects. Eur J Echocardiogr 2010;11:283289.
  • 37
    Garot P, Pascal O, Simon M et al. Usefulness of combined quantitative assessment of myocardial perfusion and velocities by myocardial contrast and doppler tissue echocardiography during coronary blood flow reduction. J Am Soc Echocardiogr 2003;16:18.
  • 38
    Lakhani M, Fein S. Effects of obesity and subsequent weight reduction on left ventricular function. Cardiol Rev 2011;19:14.
  • 39
    Paulino EC, Ferreira JC, Bechara LR et al. Exercise training and caloric restriction prevent reduction in cardiac Ca2+-handling protein profile in obese rats. Hypertension 2010;56:629635.
  • 40
    Shivu GN, Abozguia K, Phan TT et al. Increased left ventricular torsion in uncomplicated type 1 diabetic patients: the role of coronary microvascular function. Diabetes Care 2009;32:17101712.