SEARCH

SEARCH BY CITATION

References

  • ANSANAY, H., SEBBEN, M., BOCKAERT, J. & DUMUIS, A. (1992). Characterization of homologous 5-hydroxytryptamine 4 receptor desensitization in colliculi neurons. Mol. Pharmacol., 42, 808816.
  • BENDER, E., PINDON, A., VAN OERS, I., ZHANG, Y.B., GOMMEREN, W., VERHASSELT, P., JURZAK, M., LEYSEN, J. & LUYTEN, W. (2000). Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant. J. Neurochem., 74, 478489.
  • BLONDEL, O., GASTINEAU, M., DAHMOUNE, Y., LANGLOIS, M. & FISCHMEISTER, R. (1998). Cloning, expression and pharmacology of four human 5-HT4 receptor isoforms produced by alternative splicing in the carboxyl terminus. J. Neurochem., 70, 22522261.
  • BLONDEL, O., VANDECASTEELE, G., GASTINEAU, M., LECLERC, S., DAHMOUNE, Y., LANGLOIS, M. & FISCHMEISTER, R. (1997). Molecular and functional characterization of a 5-HT4 receptor cloned from human atrium. FEBS Lett., 412, 465474.
  • BUNEMANN, M. & HOSEY, M.M. (1999). G-protein coupled receptor kinases as modulators of G-protein signaling. J. Physiol., 517, 523.
  • BUNEMANN, M., LEE, K.B., PALS-RYLAARSDAM, R., ROSEBERRY, A.G. & HOSEY, M.M. (1999). Desensitization of G-protein-coupled receptors in the cardiovascular system. Ann. Rev. of Physiol., 61, 169192.
  • CHEN, Y., HARRY, A., LI, J., SMIT, M.J., BAI, X., MAGNUSSON, R., PIERONI, J.P., WENG, G. & IYENGAR, R. (1997). Adenylyl cyclase 6 is selectively regulated by protein kinase A phosphorylation in a region involved in Gαs stimulation. Proc. Natl. Acad. Sci. U.S.A., 94, 1410014104.
  • CLAEYSEN, S., FAYE, P., SEBBEN, M., LEMAIRE, S., BOCKAERT, J. & DUMUIS, A. (1997). Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase. NeuroReport, 8, 31893196.
  • CLAEYSEN, S., SEBBEN, M., BECAMEL, C., BOCKAERT, J. & DUMUIS, A. (1999). Novel brain-specific 5-HT4 receptor splice variants show marked constitutive activity: role of the C-terminal intracellular domain. Mol. Pharmacol., 55, 910920.
  • DEFER, N., BEST-BELPOMME, M. & HANOUNE, J. (2000). Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase. Am. J. Physiol., 279, F400F416.
  • DE PONTI, F. & TONINI, M. (2001). Irritable bowel syndrome - New agents targeting serotonin receptor subtypes. Drugs, 61, 317332.
  • GERHARDSTEIN, B., PURI, T., CHIEN, A.J. & HOSEY, M.M. (1999). Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the β2 subunit of L-type voltage-dependent calcium channels. Biochemistry, 38, 1036110370.
  • HEDGE, S. & EGLEN, R. (1996). Peripheral 5-HT4 receptors. FASEB J., 10, 13981407.
  • IWAMI, G., KAWABE, J., EBINA, T., CANNON, P.J., HOMCY, C.J. & ISHIKAWA, Y. (1995). Regulation of adenylyl cyclase by protein kinase A. J. Biol. Chem., 270, 1248112484.
  • KAUMANN, A.J. (1994). Do human atrial 5-HT4 receptors mediate arrhythmias Trends Pharmacol. Sci., 15, 451455.
  • KAUMANN, A.J., SANDERS, L., BROWN, A.M., MURRAY, K.J. & BROWN, M.J. (1990). A 5-hydroxytryptamine receptor in human atrium. Br. J. Pharmacol., 100, 879885.
  • KENNELLY, P.J. & KREBS, E.G. (1991). Consensus sequences as substrate specificity determinants for protein kinases and protein phosphates. J. Biol. Chem., 266, 1555515558.
  • KRUPNICK, J.G. & BENOVIC, J.L. (1998). The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Ann. Rev. Pharmaco. Toxicol., 38, 289319.
  • LEFKOWITZ, R.J. (1998). G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J. Biol. Chem., 273, 1867718680.
  • MARCHETTI, E., DUMUIS, A., BOCKAERT, J., SOUMIREU-MOURAT, B. & ROMAN, F.S. (2000). Differential modulation of the 5-HT(4) receptor agonists and antagonist on rat learning and memory. Neuropharmacology, 39, 20172027.
  • MAY, L.G., JOHNSON, S., KREBS, S., NEWMAN, A. & ARONSTAM, R.S. (1999). Involvement of protein kinase C and protein kinase A in the muscarinic receptor signalling pathways mediating phospholipase C activation, arachidonic acid release and calcium mobilisation. Cell. Signal., 11, 179187.
  • MEDHURST, A.D., LEZOUALCH'H, F., FISCHMEISTER, R., MIDDLEMISS, D.N. & SANGER, G.J. (2001). Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT–PCR. Mol. Brain Res., 90, 125134.
  • MIALET, J., BERQUE-BESTEL, I., EFTEKHARI, P., GASTINEAU, M., GINER, M., DAHMOUNE, Y., DONZEAU-GOUGE, P., HOEBEKE, J., LANGLOIS, M., SICSIC, S., FISCHMEISTER, R. & LEZOUALC'H, F. (2000a). Isolation of the serotoninergic 5-HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6-glial and CHO cells. Br. J. Pharmacol., 129, 771781.
  • MIALET, J., BERQUE-BESTEL, I., SICSIC, S., LANGLOIS, M., FISCHMEISTER, R. & LEZOUALC'H, F. (2000b). Pharmacological characterization of the human 5-HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells. Br. J. Pharmacol., 131, 827835.
  • MOFFETT, S., ROUSSEAU, G., LAGACE, M. & BOUVIER, M. (2001). The palmitoylation state of the β2-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and β-adrenergic receptor kinase involved in its phosphorylation and desensitization. J. Neurochem., 76, 269279.
  • MUNDELL, S.J. & KELLY, E. (1998). The effect of inhibitors of receptor internalization on the desensitization and resensitization of three Gs-coupled receptor responses. Br. J. Pharmacol., 125, 15941600.
  • PINDON, A., VAN HECKE, G., VAN GOMPEL, P., LESAGE, A.S., LEYSEN, J.E. & JURZAK, M. (2002). Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Gαs- and Gαi/o-proteins. Mol. Pharmacol., 61, 8596.
  • PIPPIG, S., ANDEXINGER, S. & LOHSE, M.J. (1995). Sequestration and recycling of β2-adrenergic receptors permit receptor resensitization. Mol. Pharmacol., 47, 666676.
  • PITCHER, J.A., FREEDMAN, N.J. & LEFKOWITZ, R.J. (1998). G protein-coupled receptor kinases. Annu. Rev. Biochem., 67, 653692.
  • REYNOLDS, G.P., MASON, L., MELDRUM, A., DE KECZER, S., PARNES, H. & WONG, E.H.F. (1995). 5-hydroxytryptamine 5-HT4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases. Br. J. Pharmacol., 114, 993998.
  • ROBERT, S.J., ZUGAZA, J.L., FISCHMEISTER, R., GARDIER, A.M. & LEZOUALC'H, F. (2001). The human serotonin 5-HT4 receptor regulates secretion of non amyloidogenic precursor protein. J. Biol. Chem., 276, 44814488.
  • RONDÉ, P., ANSANAY, H., DUMUIS, A., MILLER, R. & BOCKAERT, J. (1995). Homologous desensitization of 5-hydroxytryptamine4 receptors in rat esophagus: functional and second messenger studies. J. Pharmacol. Exp. Ther., 272, 977983.
  • SEIBOLD, A., WILLIAMS, B., HUANG, Z., FRIEDMAN, J., MOORE, R.H., KNOLL, B.J. & CLARK, R.B. (2000). Localization of the sites mediating desensitization of the β2-adrenergic receptor by the GRK pathway. Mol. Pharmacol., 58, 11621173.
  • SMEETS, R.L., FOURAUX, M.A., VAN EMST-DE VRIES, S.E., DE PONT, J.J. & WILLEMS, P.H. (1998). Protein kinase C-mediated inhibition of transmembrane signalling through CCK(A) and CCK(B) receptors. Br. J. Pharmacol., 123, 11891197.
  • TOULLEC, D., PIANETTI, P., COSTE, H., BELLEVERGUE, P., GRAND-PERRET, T., AJAKANE, M., BAUDET, V., BOISSIN, P., BOURSIER, E. & LORIOLLE, F. (1991). The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem., 266, 1577115781.
  • VAN DEN WYNGAERT, I., GOMMEREN, W., VERHASSELT, P., JURZAK, M., LEYSEN, J., LUYTEN, W. & BENDER, E. (1997). Cloning and expression of a human serotonin 5-HT4 receptor cDNA. J. Neurochem., 69, 18101819.
  • VILARÓ, M.T., DOMÉNECH, T., PALACIOS, J.M. & MENGOD, G. (2002). Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxyl terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variants. Neuropharmacology, 42, 6073.