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  • AKERMAN, S., WILLIAMSON, D.J., KAUBE, H. & GOADSBY, P.J. (2002). Nitric oxide synthase inhibitors can antagonise neurogenic and calcitonin gene-related peptide induced dilation of dural meningeal vessels. Br. J. Pharmacol., 137, 6268.
  • ARMITAGE, P & BERRY, G (1994). Statistical Methods in Medical Research, 3rd edn. Oxford: Blackwell Science.
  • BAHRA, A., MATHARU, M.S., BUCHEL, C., FRACKOWIAK, R.S.J. & GOADSBY, P.J. (2001). Brainstem activation specific to migraine headache. Lancet, 357, 10161017.
  • BEREITER, D.A., BEREITER, D.F. & HATHAWAY, C.B. (1996). The NMDA receptor antagonist MK-801 reduces Fos-like immunoreactivity in central trigeminal neurons and blocks select endocrine and autonomic responses to corneal stimulation in the rat. Pain, 64, 179189.
  • BLOOM, F.E. (1974). To spritz or not to spritz: the doubtful value of aimless iontophoresis. Life Sci., 14, 18191834.
  • CARLTON, S.M., HARGETT, G.L. & COGGESHALL, R.E. (2001). Localization of metabotropic glutamate receptors 2/3 on primary afferent axons in the rat. Neuroscience, 105, 957969.
  • CHOKSI, T., HAY, D.L., LEGON, S., POYNER, D.R., HAGER, S., BLOOM, S.R. & SMITH, D.M. (2002). Comparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines. Br. J. Pharmacol., 136, 784792.
  • COLLIN, E., FRECHILLA, D., POHL, M., BOURGOIN, S., LE BARS, D., HAMON, M. & CESSELIN, F. (1993). Opioid control of the release of calcitonin gene-related peptide-like material from the rat spinal cord in vivo. Brain Res., 609, 211222.
  • CUMBERBATCH, M.J., HILL, R.G. & HARGREAVES, R.J. (1997). Rizatriptan has central antinociceptive effects against durally evoked responses. Eur. J. Pharmacol., 328, 3740.
  • CUTRER, F.M., LIMMROTH, V., AYATA, G. & MOSKOWITZ, M.A. (1995). Attenuation by valproate of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin. Br. J. Pharmacol., 116, 31993204.
  • DE FUSCO, M., MARCONI, R., SILVESTRI, L., ATORINO, L., RAMPOLDI, L., MORGANTE, L., BALLABIO, A., ARIDON, P. & CASARI, G. (2003). Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump α2 subunit associated with familial hemiplegic migraine type 2. Nat. Genet., 33, 192196.
  • DE VRIES, P., VILLALON, C.M. & SAXENA, P.R. (1999). Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy. Eur. J. Pharmacol., 375, 6174.
  • DENNIS, T., FOURNIER, A., CADIEUX, A., POMERLEAU, F., JOLICOEUR, F.B., ST. PIERRE, S. & QUIRION, R. (1990). hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery. J. Pharmacol. Exp. Ther., 254, 123128.
  • DOODS, H., HALLERMAYER, G., WU, D., ENTZEROTH, M., RUDOLF, K., ENGEL, W. & EBERLEIN, W. (2000). Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist. Br. J. Pharmacol., 129, 420423.
  • EDVINSSON, L., EKMAN, R., JANSEN, I., McCULLOCH, J. & UDDMAN, R. (1987). Calcitonin gene-related peptide and cerebral blood vessels: distribution and vasomotor effects. J. Cereb. Blood Flow Metabol., 7, 720728.
  • EDVINSSON, L. & GOADSBY, P.J. (1998). Neuropeptides in headache. Eur. J. Neurol., 5, 329341.
  • EKBOM, K. & THE SUMATRIPTAN CLUSTER HEADACHE STUDY GROUP (1991). Treatment of acute cluster headache with sumatriptan. N. Engl. J. Med., 325, 322326.
  • FANCIULLACCI, M., ALESSANDRI, M., FIGINI, M., GEPPETTI, P. & MICHELACCI, S. (1995). Increase in plasma calcitonin gene-related peptide from extracerebral circulation during nitroglycerin-induced cluster headache attack. Pain, 60, 119123.
  • FEINDEL, W., PENFIELD, W. & McNAUGHTON, F. (1960). The tentorial nerves and localization of intracranial pain in man. Neurology, 10, 555563.
  • FERRARI, M.D., ROON, K.I., LIPTON, R.B. & GOADSBY, P.J. (2001). Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet, 358, 16681675.
  • FRIBERG, L., OLESEN, J., IVERSEN, H.K. & SPERLING, B. (1991). Migraine pain associated with middle cerebral artery dilatation: reversal by sumatriptan. Lancet, 338, 1317.
  • FUSSEY, I.F., KIDD, C. & WHITWAM, J.G. (1970). The differentiation of axonal and soma-dendritic spike activity. Pflugers Arch., 321, 283292.
  • GALLAI, V., SARCHIELLI, P., FLORIDI, A., FRANCESCHINI, M., CODINI, M., TREQUATTRINI, A. & PALUMBO, R. (1995). Vasoactive peptides levels in the plasma of young migraine patients with and without aura assessed both interictally and ictally. Cephalalgia, 15, 384390.
  • GOADSBY, P.J. (1993). Inhibition of calcitonin gene-related peptide by h-CGRP(8–37) antagonizes the cerebral dilator response from nasociliary nerve stimulation in the cat. Neurosci. Lett., 151, 1316.
  • GOADSBY, P.J. (2000). The pharmacology of headache. Prog. Neurobiol., 62, 509525.
  • GOADSBY, P.J., AKERMAN, S. & STORER, R.J. (2001). Evidence for postjunctional serotonin (5-HT1) receptors in the trigeminocervical complex. Ann. Neurol., 50, 804807.
  • GOADSBY, P.J. & EDVINSSON, L. (1993). The trigeminovascular system and migraine: studies characterizing cerebrovascular and neuropeptide changes seen in humans and cats. Ann. Neurol., 33, 4856.
  • GOADSBY, P.J. & EDVINSSON, L. (1994a). Human in vivo evidence for trigeminovascular activation in cluster headache. Brain, 117, 427434.
  • GOADSBY, P.J. & EDVINSSON, L. (1994b). Peripheral and central trigeminovascular activation in cat is blocked by the serotonin (5HT)-1D receptor agonist 311C90. Headache, 34, 394399.
  • GOADSBY, P.J., EDVINSSON, L. & EKMAN, R. (1988). Release of vasoactive peptides in the extracerebral circulation of man and the cat during activation of the trigeminovascular system. Ann. Neurol., 23, 193196.
  • GOADSBY, P.J., EDVINSSON, L. & EKMAN, R. (1990). Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann. Neurol., 28, 183187.
  • GOADSBY, P.J. & HOSKIN, K.L. (1996). Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites a therapeutic target in migraine? Pain, 67, 355359.
  • GOADSBY, P.J. & HOSKIN, K.L. (1997). The distribution of trigeminovascular afferents in the nonhuman primate brain Macaca nemestrina: a c-fos immunocytochemical study. J. Anat., 190, 367375.
  • GOADSBY, P.J. & LAMBERT, G.A. (1986). An interactive, readily transportable program using a log/logit transformation for the analysis of radioimmunoassay data. Comput. Methods Programs Biomed., 23, 263268.
  • GOADSBY, P.J., LIPTON, R.B. & FERRARI, M.D. (2002). Migraine—current understanding and treatment. N. Engl. J. Med., 346, 257270.
  • GOADSBY, P.J. & ZAGAMI, A.S. (1991). Stimulation of the superior sagittal sinus increases metabolic activity and blood flow in certain regions of the brainstem and upper cervical spinal cord of the cat. Brain, 114, 10011011.
  • HELLIER, M., BOERS, P. & LAMBERT, G.A. (1990). Fabrication of a metal-cored multi-barrelled microiontophoresis assembly. J. Neurosci. Meth., 32, 5561.
  • HILL, R.G. & SALT, T.E. (1982). An iontophoretic study of the responses of rat caudal trigeminal nucleus neurones to non-noxious mechanical sensory stimuli. J. Physiol., 327, 6578.
  • HOSKIN, K.L. & GOADSBY, P.J. (1998). Comparison of a more and less lipophilic serotonin (5HT1B/1D) agonists in a model of trigeminovascular nociception in cat. Exp. Neurol., 150, 4551.
  • HOSKIN, K.L. & GOADSBY, P.J. (1999). Exposure and isolation of the superior sagittal sinus elicits Fos in the trigeminal nucleus caudalis and dorsal horn of the cervical spinal cord: how long should you wait? Brain Res., 824, 133135.
  • HOSKIN, K.L., KAUBE, H. & GOADSBY, P.J. (1996). Central activation of the trigeminovascular pathway in the cat is inhibited by dihydroergotamine. A c-Fos and electrophysiology study. Brain, 119, 249256.
  • HOSKIN, K.L., ZAGAMI, A. & GOADSBY, P.J. (1999). Stimulation of the middle meningeal artery leads to Fos expression in the trigeminocervical nucleus: a comparative study of monkey and cat. J. Anat., 194, 579588.
  • HOU, M., KANJE, M., LONGMORE, J., TAJTI, J., UDDMAN, R. & EDVINSSON, L. (2001). 5-HT1B and 5-HT1D receptors in the human trigeminal ganglion: co-localization with calitonin gene-related peptide, substance P and nitric oxide synthase. Brain Res., 909, 112120.
  • HU, J.W., DOSTROVSKY, J.O. & SESSLE, B.J. (1981). Functional properties of neurons in cat trigeminal subnucleus caudalis (medullary dorsal horn). I. Responses to oral–facial noxious and nonnoxious stimuli and projections to thalamus and subnucleus oralis. J. Neurophysiol., 45, 173192.
  • KAUBE, H., HOSKIN, K.L. & GOADSBY, P.J. (1993a). Inhibition by sumatriptan of central trigeminal neurones only after blood–brain barrier disruption. Br. J. Pharmacol., 109, 788792.
  • KAUBE, H., KEAY, K.A., HOSKIN, K.L., BANDLER, R. & GOADSBY, P.J. (1993b). Expression of c-Fos-like immunoreactivity in the caudal medulla and upper cervical cord following stimulation of the superior sagittal sinus in the cat. Brain Res., 629, 95102.
  • LIMMROTH, V., MAY, A., AUERBACH, P., WOSNITZA, G., EPPE, T. & DIENER, H.C. (1996). Changes in cerebral blood flow velocity after treatment with sumatriptan or placebo and implications for the pathophysiology of migraine. J. Neurol. Sci., 138, 6065.
  • MA, Q.-P., HILL, R. & SIRINATHSINGHJI, D. (2001). Colocalization of CGRP with 5-HT1B/1D receptors and substance P in trigeminal ganglion neurons in rats. Eur. J. Neurosci., 13, 20992104.
  • MANDELBROD, I., FELDMAN, S. & WERMAN, R. (1974). Inhibition of firing is the primary effect of microelectrophoresis of cortisol to units in the rat tuberal hypothalamus. Brain Res., 80, 303315.
  • MANDELBROD, I., FELDMAN, S. & WERMAN, R. (1983). Mediobasal hypothalamic neurons are excited by the iontophoretic application of sodium. Brain Res., 273, 3544.
  • MATHARU, M., BARTSCH, T., WARD, N., FRACKOWIAK, R., WEINER, R. & GOADSBY, P. (2003). Central neuromodulation with implanted suboccipital stimulators in patients with chronic migraine. Cephalalgia, 23, 655.
  • MAY, A., BAHRA, A., BÜCHEL, C., FRACKOWIAK, R.S.J. & GOADSBY, P.J. (1998). Hypothalamic activation in cluster headache attacks. Lancet, 352, 275278.
  • McLATCHIE, L.M., FRASER, N.J., MAIN, M.J., WISE, A., BROWN, J., THOMPSON, N., SOLARI, R., LEE, M.G. & FOORD, S.M. (1998). RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature, 393, 333339.
  • MITSIKOSTAS, D.D., SANCHEZ del RIO, M., WAEBER, C., HUANG, Z., CUTRER, F.M. & MOSKOWITZ, M.A. (1999). Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis. Br. J. Pharmacol., 127, 623630.
  • MITSIKOSTAS, D.D., SANCHEZ del RIO, M., WAEBER, C., MOSKOWITZ, M.A. & CUTRER, F.M. (1998). The NMDA receptor antagonist MK-801 reduces capsaicin-induced c-fos expression within rat trigeminal nucleus caudalis. Pain, 76, 239248.
  • MORENO, M.J., ABOUNADER, R., HÉBERT, E., DOODS, H. & HAMEL, E. (2002). Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment. Neuropharmacology, 42, 568576.
  • MOSKOWITZ, M.A. & CUTRER, F.M. (1993). SUMATRIPTAN: a receptor-targeted treatment for migraine. Ann. Rev. Med., 44, 145154.
  • NAGLER, J., CONFORTI, N. & FELDMAN, S. (1973). Alterations produced by cortisol in the spontaneous activity and responsiveness to sensory stimuli of single cells in the tuberal hypothalamus of the rat. Neuroendocrinology, 12, 5266.
  • OLESEN, J. (1991). Cerebral and extracranial circulatory disturbances in migraine: pathophysiological implications. Cerebrovasc. Brain Metab. Rev., 3, 128.
  • OLESEN, J., DIENER, H.-C., HUSSTEDT, I.W., GOADSBY, P.J., HALL, D., MEIER, U., POLLENTIER, S. & LESKO, L.M. (2003). Calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS is effective in the treatment of migraine attacks. Cephalalgia, 23, 579.
  • OLESEN, J., FRIBERG, L., SKYHOJ-OLSEN, T., IVERSEN, H.K., LASSEN, N.A., ANDERSEN, A.R. & KARLE, A. (1990). Timing and topography of cerebral blood flow, aura, and headache during migraine attacks. Ann. Neurol., 28, 791798.
  • OPHOFF, R.A., TERWINDT, G.M., VERGOUWE, M.N., Van EIJK, R., OEFNER, P.J., HOFFMAN, S.M.G., LAMERDIN, J.E., MOHRENWEISER, H.W., BULMAN, D.E., FERRARI, M., HAAN, J., LINDHOUT, D., Van OMMEN, G.-J.B., HOFKER, M.H., FERRARI, M.D. & FRANTS, R.R. (1996). Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell, 87, 543552.
  • PANNETON, W.M. & BURTON, H. (1981). Corneal and periocular representation within the trigeminal sensory complex in the cat studied with transganglionic transport of horseradish peroxidase. J. Comp. Neurol., 199, 327344.
  • PETERSEN, K.A., BIRK, S., LASSEN, L.H., KRUUSE, C., JONASSEN, O. & OLESEN, J. (2003a). The novel CGRP-antagonist, BIBN4096BS does not affect the cerebral hemodynamics in healthy volunteers. Cephalalgia, 23, 729.
  • PETERSEN, K.A., LASSEN, L.H., BIRK, S. & OLESEN, J. (2003b). The effect of the nonpeptide CGRP-antagonist, BIBN406BS on human-alphaCGRP induced headache and hemodynamics in healthy volunteers. Cephalalgia, 23, 725.
  • POWELL, K.J., MA, W., SUTAK, M., DOODS, H., QUIRION, R. & JHAMANDAS, K. (2000). Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists. Br. J. Pharmacol., 131, 875884.
  • SALT, T.E. & HILL, R.G. (1982). Differentiation of excitatory amino acid receptors in the rat caudal trigeminal nucleus: a microiontophoretic study. Neuropharmacology, 21, 385390.
  • STORER, R.J., AKERMAN, S., CONNOR, H.E. & GOADSBY, P.J. (2001a). 4991W93, a potent blocker of neurogenic plasma protein extravasation, inhibits trigeminal neurons at 5-hydroxytryptamine (5-HT1B/1D) agonist doses. Neuropharmacology, 40, 911917.
  • STORER, R.J., AKERMAN, S. & GOADSBY, P.J. (2001b). GABA receptors modulate trigeminovascular nociceptive neurotransmission in the trigeminocervical complex. Br. J. Pharmacol., 134, 896904.
  • STORER, R.J., BUTLER, P., HOSKIN, K.L. & GOADSBY, P.J. (1997). A simple method, using 2-hydroxypropyl-β-cyclodextrin, of administering α-chloralose at room temperature. J. Neurosci. Meth., 77, 4953.
  • STORER, R.J. & GOADSBY, P.J. (1997). Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat. Brain, 120, 21712177.
  • STORER, R.J. & GOADSBY, P.J. (1999). Trigeminovascular nociceptive transmission involves N-methyl-D-aspartate and non-N-methyl-D-aspartate glutamate receptors. Neuroscience, 90, 13711376.
  • TALLAKSEN-GREENE, S.J., YOUNG, A.B., PENNEY, J.B. & BEITZ, A.J. (1992). Excitatory amino acid binding sites in the trigeminal principal sensory and spinal trigeminal nuclei of the rat. Neurosci. Lett., 141, 7983.
  • WAHL, M., SCHILLING, L., PARSONS, A.A. & KAUFMANN, A. (1994). Involvement of calcitonin gene-related peptide (CGRP) and nitric oxide (NO) in the pial artery dilatation elicited by cortical spreading depression. Brain Res., 637, 204210.
  • WEILLER, C., MAY, A., LIMMROTH, V., JUPTNER, M., KAUBE, H., SCHAYCK, R.V., COENEN, H.H. & DIENER, H.C. (1995). Brain stem activation in spontaneous human migraine attacks. Nat. Med., 1, 658660.
  • WILLIAMSON, D.J., HARGREAVES, R.J., HILL, R.G. & SHEPHEARD, S.L. (1997). Intravital microscope studies on the effects of neurokinin agonists and calcitonin gene-related peptide on dural blood vessel diameter in the anaesthetized rat. Cephalalgia, 17, 518524.
  • WOLFF, H.G. (1948). Headache and Other Head Pain. New York: Oxford University Press.
  • YU, L.-C., HANSSON, P. & LUNDEBERG, T. (1996). The calcitonin gene-related peptide antagonist CGRP8–37 increases the latency to withdrawal responses bilaterally in rats with unilateral experimental mononeuropathy, an effect reversed by naloxone. Neuroscience, 71, 523531.