• AHLQVIST, J. (2000). Swelling of synovial joints – an anatomical, physiological and energy metabolical approach. Pathophysiology, 7, 119.
  • BÖCKMANN, S., SEEP, J. & JONES, L. (2001). Delay of neutrophil apoptosis by the neuropeptide substance P: involvement of caspase cascade. Peptides, 22, 661670.
  • BULLING, D.G., KELLY, D., BOND, S., MCQUEEN, D.S. & SECKL, J.R. (2001). Adjuvant-induced joint inflammation causes a very rapid transcription of beta-preprotachykinin and alpha-CGRP genes in innervating sensory ganglia. J. Neurochem., 77, 372382.
  • CAO, T., GERARD, N.P. & BRAIN, S.D. (1999). Use of NK1 knockout mice to analyze substance P-induced edema formation. Am. J. Physiol., 277, R476R481.
  • CAO, T., PINTER, E., AL-RASHED, S., GERARD, N., HOULT, R. & BRAIN, S.D. (2000). Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice. J. Immunol., 164, 54245429.
  • CAO, Y.Q., MANTYH, P.W., CARLSON, E.J., GILLESPIE, A.M., EPSTEIN, C.J. & BASBAUM, A.I. (1998). Primary afferent tachykinins are required to experience moderate to intense pain. Nature, 392, 390394.
  • DE FELIPE, C., HERRERO, J.F., O'BRIEN, J.A., PALMER, J.A., DOYLE, C.A., SMITH, A.J., LAIRD, J.M., BELMONTE, C., CERVERO, F. & HUNT, S.P. (1998). Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature, 392, 394397.
  • FERRELL, W.R. & RUSSELL, N.J. (1986). Extravasation in the knee induced by antidromic stimulation of articular C fibre afferents of the anaesthetized cat. J. Physiol., 379, 407416.
  • HAFSTROM, I., GYLLENHAMMER, H., PALMBLAD, J. & RINGERTZ, B. (1989). Substance P activates and modulates neutrophil oxidative metabolism and aggregation. J. Rheumatol., 16, 10331037.
  • IGNATAVICIUS, D.D. (2001). Rheumatoid arthritis and the older adult. Geriatr. Nurs., 22, 139142.
  • KIDD, B.L., CRUWYS, S.C., GARRETT, N.E., MAPP, P.I., JOLLIFFE, V.A. & BLAKE, D.R. (1995). Neurogenic influences on contralateral responses during experimental rat monoarthritis. Brain Res., 688, 7276.
  • KIDD, B.L., INGLIS, J.J., VETSIKA, K., HOOD, V.C., DE FELIPE, C., BESTER, H., HUNT, S.P. & CRUWYS, S.C. (2003). Inhibition of inflammation and hyperalgesia in NK-1 receptor knock-out mice. Neuroreport, 14, 21892192.
  • LEVINE, J.D., DARDICK, S.J., ROIZEN, M.F., HELMS, C. & BASBAUM, A.L. (1986). Contribution of sensory afferents and sympathetic efferents to joint injury in experimental arthritis. J. Neurosci., 6, 34233429.
  • LU, B., FIGINI, M., EMANUELI, C., GEPPETTI, P., GRADY, E.F., GERARD, N.P., ANSELL, J., PAYAN, D.G., GERARD, C. & BUNNETT, N. (1997). The control of microvascular permeability and blood pressure by neutral endopeptidase. Nat. Med., 3, 904907.
  • NIISSALO, S., HUKKANEN, M., IMAI, S., TORNWALL, J. & KONTTINEN, Y.T. (2002). Neuropeptides in experimental and degenerative arthritis. Ann. NY. Acad. Sci., 969, 384399.
  • PLANTE, G.E., CHAKIR, M., ETTAOUIL, M., LEHOUX, S. & SIROIS, P. (1996). Consequences of alteration in capillary permeability. Can. J. Physiol. Pharmacol., 74, 824833.
  • QUINLAN, K.L., SONG, I.S., NAIK, S.M., LETRAN, E.L., OLREUD, J.E., BUNNETT, N.W., ARMSTRONG, C.A., CAUGHMAN, S.W. & ANSEL, J.C. (1999). VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically upregulated by substance P. J. Immunol., 16, 16561661.
  • ROTHSCHILD, B.M. & MASI, A.T. (1982). Pathogenesis of rheumatoid arthritis: a vascular hypothesis. Semin. Arthritis Rheum., 12, 1131.
  • SAKAI, K., MATSUNO, H., TSUJI, H. & TOHYAMA, M. (1998). Substance P receptor gene expression in synovial fluid in rheumatoid arthritis and osteoarthritis. Scand. J. Rheumatol., 27, 135141.
  • SCOTT, D.T., LAM, F.Y. & FERRELL, W.R. (1992). Acute inflammation enhances substance P-induced plasma protein extravasation in the rat knee joint. Regul. Peptides, 39, 227235.
  • SEGOND VON BANCHET, G., PETROW, P.K., BRAUER, R. & SCHAIBLE, H.G. (2000). Monoarticular antigen-induced arthritis leads to a pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats. Arthritis Res., 2, 424427.
  • SKIDGEL, R.A., ENGELBRECHT, S., JOHNSON, A.R. & ERDOS, E.G. (1984). Hydrolysis of substance P and neurotensin by converting enzyme and neutral endopeptidase. Peptides, 5, 769776.
  • SZEKANECZ, Z., HALLORAN, M.M., VOLIN, M.V., WOODS, J.M., STRIETER, R.M., HAINES, G., KUNKEL, S.L., BURDICK, M.D. & KOCH, A.E. (2000). Temporal expression of inflammatory cytokines and chemokines in rat adjuvant-induced arthritis. Arthritis Rheum., 43, 12661277.
  • VON ESSEN, S.G., RENNARD, S.I., O'NEILL, D., ERTL, R.F., ROBBINS, R.A., KOYAMA, S. & RUBENSTEIN, I. (1992). Bronchial epithelial cells release neutrophil chemotactic activity in response to tachykinins. Am. J. Physiol., 263, L226L231.