• Adini I, Rabinovitz I, Sun JF, Prendergast GC, Benjamin LE (2003) RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development. Genes Dev 17: 27212732
  • Bayless KJ, Davis GE (2004) Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. J Biol Chem 279: 1168611695
  • Carmeliet P (2000) Mechanisms of angiogenesis and arteriogenesis. Nat Med 6: 389395
  • Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N (1998) Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 273: 3033630343
  • Gille H, Kowalski J, Yu L, Chen H, Pisabarro MT, Davis-Smyth T, Ferrara N (2000) A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration. EMBO J 19: 40644073
  • Gitlin JD, D'Amore PA (1983) Culture of retinal capillary cells using selective growth media. Microvasc Res 26: 7480
  • Hamada K, Sasaki T, Koni PA, Natsui M, Kishimoto H, Sasaki J, Yajima N, Horie Y, Hasegawa G, Naito M, Miyazaki J, Suda T, Itoh H, Nakao K, Mak TW, Nakano T, Suzuki A (2005) The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev 19: 20542065
  • Im E, Venkatakrishnan A, Kazlauskas A (2005) Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells. Mol Biol Cell 16: 34883500
  • Irvine R (2000) Nuclear lipid signaling. Sci STKE 2000: RE1
  • Lawson ND, Mugford JW, Diamond BA, Weinstein BM (2003) Phospholipase C gamma-1 is required downstream of vascular endothelial growth factor during arterial development. Genes Dev 17: 13461351
  • Liao HJ, Kume T, McKay C, Xu MJ, Ihle JN, Carpenter G (2002) Absence of erythrogenesis and vasculogenesis in Plcg1-deficient mice. J Biol Chem 277: 93359341
  • Matsumoto T, Claesson-Welsh L (2001) VEGF receptor signal transduction. Sci STKE 2001: RE21
  • Ory DS, Neugeboren BA, Mulligan RC (1996) A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes. Proc Natl Acad Sci USA 93: 1140011406
  • Plattner R, Irvin BJ, Guo S, Blackburn K, Kazlauskas A, Abraham RT, York JD, Pendergast AM (2003) A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nat Cell Biol 5: 309319
  • Qi JH, Matsumoto T, Huang K, Olausson K, Christofferson R, Claesson-Welsh L (1999) Phosphoinositide 3 kinase is critical for survival, mitogenesis and migration but not for differentiation of endothelial cells. Angiogenesis 3: 371380
  • Rahimi N, Kazlauskas A (1999) A role for cadherin-5 in regulation of vascular endothelial growth factor receptor 2 activity in endothelial cells. Mol Biol Cell 10: 34013407
  • Rasmussen HS, Rasmussen CS, Durham RG, King CR, Wei L (2001) Looking into anti-angiogenic gene therapies for disorders of the eye. Drug Discov Today 6: 11711175
  • Sakurai Y, Ohgimoto K, Kataoka Y, Yoshida N, Shibuya M (2005) Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice. Proc Natl Acad Sci USA 102: 10761081
  • Saunders WB, Bayless KJ, Davis GE (2005) MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. J Cell Sci 118: 23252340
  • Shimizu K, Oku N (2004) Cancer anti-angiogenic therapy. Biol Pharm Bull 27: 599605
  • Takahashi T, Yamaguchi S, Chida K, Shibuya M (2001) A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells. EMBO J 20: 27682778
  • Valius M, Bazenet C, Kazlauskas A (1993) Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol Cell Biol 13: 133143
  • Valius M, Kazlauskas A (1993) Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73: 321334
  • Wang D, Huang HJ, Kazlauskas A, Cavenee WK (1999) Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res 59: 14641472
  • Weiner OD, Neilsen PO, Prestwich GD, Kirschner MW, Cantley LC, Bourne HR (2002) A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nat Cell Biol 4: 509513