Determinants of quality of life in first-episode psychosis
Version of Record online: 10 DEC 2003
Acta Psychiatrica Scandinavica
Volume 109, Issue 1, pages 46–54, January 2004
How to Cite
Malla, A. K., Norman, R. M. G., McLean, T. S., MacDonald, C., McIntosh, E., Dean-Lashley, F., Lynch, J., Scholten, D. and Ahmed, R. (2004), Determinants of quality of life in first-episode psychosis. Acta Psychiatrica Scandinavica, 109: 46–54. doi: 10.1046/j.0001-690X.2003.00221.x
- Issue online: 10 DEC 2003
- Version of Record online: 10 DEC 2003
- Accepted for publication July 15, 2003
- first-episode psychosis;
- quality of life
Objective: To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP).
Method: Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis.
Results: Patients presented with varying levels of QOL on different domains. The level of ‘general satisfaction’ was related to age of onset and social premorbid adjustment; ‘weighted index of QOL’ to social premorbid adjustment and inversely to educational premorbid adjustment; ‘social relations’ inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; ‘psychological well-being’ inversely to depression and educational premorbid adjustment; ‘activities of daily living’ to social premorbid adjustment and inversely to negative symptoms; and ‘outlook on symptoms’ to level of depression.
Conclusion: Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.