Serum lipid and lipoprotein changes induced by preparations containing low-dose ethinylestradiol plus levonorgestrel
Article first published online: 28 MAR 2003
Australian and New Zealand Journal of Obstetrics and Gynaecology
Volume 43, Issue 2, pages 145–147, April 2003
How to Cite
Kiran, G., Kiran, H. and Ekerbicer, H. C. (2003), Serum lipid and lipoprotein changes induced by preparations containing low-dose ethinylestradiol plus levonorgestrel. Australian and New Zealand Journal of Obstetrics and Gynaecology, 43: 145–147. doi: 10.1046/j.0004-8666.2003.00033.x
- Issue published online: 28 MAR 2003
- Article first published online: 28 MAR 2003
- Received 25 September 2002; accepted 19 November 2002.
- lipid changes;
- low-dose monophasic combination oral contraceptive
The purpose of the present study was to evaluate the effects on lipid metabolism of a new low-dose monophasic combination oral contraceptive with 100 µg levonorgestrel and 20 µg ethinylestradiol. Sixty healthy women aged 18–45 years were administered the medication during three cycles. The study participants were screened for lipid changes. The differences in cholesterol and triglyceride levels were not statistically significant, but high-density lipoprotein levels were significantly lower and low-density lipoprotein levels were significantly higher than the baseline. Women at risk of cardiovascular disease should be carefully monitored even when using low-dose preparations.