Evidence for an intrarenal renin-angiotensin system in the European lesser-spotted dogfish
Article first published online: 3 NOV 2003
Journal of Fish Biology
Volume 63, Issue 5, pages 1337–1340, November 2003
How to Cite
Wells, A., Anderson, W. G. and Hazon, N. (2003), Evidence for an intrarenal renin-angiotensin system in the European lesser-spotted dogfish. Journal of Fish Biology, 63: 1337–1340. doi: 10.1046/j.1095-8649.2003.00234.x
- Issue published online: 3 NOV 2003
- Article first published online: 3 NOV 2003
- (Received 1 February 2003, Accepted 8 August 2003)
- intrarenal RAS;
- Scyliorhinus canicula.
The existence of an intrarenal renin-angiotensin system (RAS) in a perfused European lesser-spotted dogfish Scyliorhinus canicula trunk preparation was examined by the inhibition of angiotensin-converting enzyme by captopril. This resulted in a glomerular diuresis, an increase in urea and chloride clearance and excretion, and an increase in transport maxima for glucose. It is proposed that these results suggest the presence of an intrarenal RAS.