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Isolation of c-myc genes from goldfish and their tissue specific expression

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†Tel.: +1 860 405 9237; fax: +1 860 405 9153; email: hzhang@uconn.edu

Abstract

One novel cellular myc gene (c-myc), GM1, was isolated from a tetraploid cyprinid, the goldfish Carassius auratus. GM1 consisted of one non-coding exon and two coding exons, presumably encoding a protein of 390 amino acid (aa) residues. The aa identity between GM1 and GM2, another c-myc previously isolated from this species, was 88·8%. Quantitative RT-PCR analysis revealed that GM1 was specifically expressed in liver and GM2 in ovary.

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