• 1
    Merki HS, Witzel L, Walt RP, et al. Day-to-day variation of 24-hour intragastric acidity. Gastroenterology 1988; 94: 88791.
  • 2
    Jamieson JR, Stein HJ, DeMeester TR, Bonavina L, Schwizer W, Hinder RA, Albertucci M. Ambulatory 24-h esophageal pH monitoring: normal values, optimal thresholds, specificity, sensitivity, and reproducibility. Am J Gastroenterol 1992; 87: 110211.
  • 3
    Quigley EMM. 24-h pH monitoring for gastroesophageal reflux disease: already standard but not yet gold? Am J Gastroenterol 1992; 87: 10715.
  • 4
    Bell NJV, Burget D, Howden CW, Wilkinson J, Hunt RH. Appropriate acid suppression for the management of gastroesophageal reflux disease. Digestion 1992; 51(Suppl. 1): 5967.
  • 5
    Bruley des Varannes S, Levy P, Lartigue S, Dellatolas F, Lemaire M, Galmiche JP. Comparison of lansoprazole with omeprazole on 24-hour intragastric pH, acid secretion and serum gastrin in healthy volunteers. Aliment Pharmacol Ther 1994; 8: 30914.
  • 6
    Hunt RH. The relationship between the control of pH and healing and symptom relief in gastro-oesophageal reflux disease. Aliment Pharmacol Ther 1995; 9(Suppl. 1): 37.
  • 7
    Hatlebakk JG, Berstad A. Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease. Clin Pharmacokinet 1996; 31: 386406.
  • 8
    Bell NJV, Hunt RH. Time to maximum effect of lansoprazole on gastric pH in normal male volunteers. Aliment Pharmacol Ther 1996; 10: 897904.
  • 9
    Dent J. Gastro-oesophageal reflux disease. Digestion 1998; 59: 43345.
  • 10
    Gardner JD, Rodriguez-Stanley S, Robinson M. Integrated acidity and the pathophysiology of GERD. Am J Gastroenterol 2001; 96: 136370.
    Direct Link:
  • 11
    Robinson M, Rodriguez-Stanley S, Ciociola AA, et al. Synergy between low dose ranitidine and antacid in reducing gastric and esophageal acidity and relieving meal-induced heartburn. Aliment Pharmacol Ther 2001; 15: 136574.
  • 12
    Moore EW, Scarlata RW. The determination of gastric acidity by the glass electrode. Gastroenterology 1965; 49: 17888.
  • 13
    Makhlouf GM, Blum AL, Moore EW. Undissociated acidity of human gastric juice. Gastroenterology 1970; 58: 34551.
  • 14
    Grimley CE, Constantinides S, Snell CC, Mills JG, Nwokolo CU. Inhibition of intragastric acidity in healthy subjects dosed with ranitidine 75 mg: a comparative study with cimetidine and placebo. Aliment Pharmacol Ther 1997; 11: 8759.
  • 15
    Cleveland WS. Visualizing Data. Summit, NJ: Hobart Press, 1993.
  • 16
    DeMeester TR, Johnson LF, Joseph GJ, Toscano MS, Hall AW, Skinner DB. Patterns of gastroesophageal reflux in health and disease. Ann Surg 1976; 84: 45970.
  • 17
    DeCastecker JS, Blackwell JN, Pryde A, Heading RC. Daytime gastro-oesophageal reflux is important in oesophagitis. Gut 1987; 28: 51926.
  • 18
    Robertson D, Aldersley M, Shepherd H, Smith CL. Patterns of acid reflux in complicated oesophagitis. Gut 1987; 28: 14848.
  • 19
    Williams MP, Sercombe J, Hamilton MI, Pounder RE. A placebo-controlled trial to assess the effects of 8 days of dosing with rabeprazole versus omperazole on 24-h intragastric acidity and plasma gastrin concentrations in young healthy subjects. Aliment Pharmacol Ther 1998; 12: 107989.DOI: 10.1046/j.1365-2036.1998.00418.x
  • 20
    Dammann HG, Fuchs W, Richter G, Burkhardt F, Wolf N, Walter TA. Lansoprazole versus omeprazole: influence on meal-stimulated gastric acid secretion. Aliment Pharmacol Ther 1997; 11: 35964.
  • 21
    Howden CW. Clinical pharmacology of omeprazole. Clin Pharmacokinet 1991; 20: 3849.
  • 22
    Andersson T. Pharmacokinetics metabolism and interactions of acid pump inhibitors. Clin Pharmacokinet 1996; 31: 928.
  • 23
    Peghini PL, Katz PO, Bracy NA, Castell DO. Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors. Am J Gastroenterol 1998; 93: 7637.
    Direct Link:
  • 24
    Katz PO, Anderson C, Khoury R, Castell DO. Gastro-oesophageal reflux associated with nocturnal gastric acid breakthrough on proton pump inhibitors. Aliment Pharmacol Ther 1998; 12: 12314.
  • 25
    Hatlebakk JG, Katz PO, Kuo B, Castell DO. Nocturnal gastric acidity and acid breakthrough on different regimens of omeprazole 40 mg daily. Aliment Pharmacol Ther 1998; 11: 123540.