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Psoriasis vulgaris coexistent with epidermolysis bullosa acquisita
Article first published online: 28 JUN 2008
DOI: 10.1046/j.1365-2133.1997.19532043.x
1365-2133/asset/cover.gif?v=1&s=413074e1e506a67a21dcc4e2de9ff9b6ce256d16 "British Journal of Dermatology")
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How to Cite
ENDO, Y., TAMURA, A., ISHIKAWA, O., MIYACHI, Y. and HASHIMOTO, T. (1997), Psoriasis vulgaris coexistent with epidermolysis bullosa acquisita. British Journal of Dermatology, 137: 783–786. doi: 10.1046/j.1365-2133.1997.19532043.x
Publication History
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Accepted for publication 5 June 1947
- Abstract
- References
- Cited By
Summary Autoimmune bullous diseases, such as bullous pemphigoid or pemphigus vulgaris. occasionally develop in psoriatic patients. In addition, a novel subepidermal bullous disease with autoantibodies against a lower lamina lucida antigen of 200kDa has recently been reported in association with psoriasis. We describe here a patient with psoriasis vulgaris who developed epidermolysis bullosa acquisita (EBA). Direct immunofluorescence revealed linear deposition of IgCl and C3 at the basement membrane zone. The patient's serum bound to the dermal side of salt-split normal human skin. However, immnumohlol analysis demonstrated that the patient's serum reacted with an EBA antigen of 290 kDa. EBA should be included in the list of autoimmune diseases associated with psoriasis vulgaris.