Clear cell syringofibroadenoma (of Mascaro) of the nail

Authors

  • B. Fouilloux,

    1. Département d’Onychologie, Service de Dermatologie, CHU St-Etienne, France
      *Service d’Anatomo-Pathologie, Hôpital Pasteur, Nice, France
    Search for more papers by this author
  • C. Perrin,

    1. Département d’Onychologie, Service de Dermatologie, CHU St-Etienne, France
      *Service d’Anatomo-Pathologie, Hôpital Pasteur, Nice, France
    Search for more papers by this author
  • M. Dutoit,

    1. Département d’Onychologie, Service de Dermatologie, CHU St-Etienne, France
      *Service d’Anatomo-Pathologie, Hôpital Pasteur, Nice, France
    Search for more papers by this author
  • F. Cambazard

    1. Département d’Onychologie, Service de Dermatologie, CHU St-Etienne, France
      *Service d’Anatomo-Pathologie, Hôpital Pasteur, Nice, France
    Search for more papers by this author

Abstract

Eccrine syringofibroadenoma (ESFA) is a rare disorder. We report the first case of ESFA of the nail apparatus, which presented as a yellow longitudinal onycholytic band of the left fourth finger over an intermittently painful subungual filamentous tumour. Histological examination showed features of ESFA with a digitate pattern of papillomatosis due to the specialized physiological longitudinal arrangement of the ridges in the nail bed. In addition, we describe a new feature of colloidal iron-positive clear cells. In our case, the presence of two types of cells with a central ductal differentiation and a significant amount of mucopolysaccharides in clear cells could suggest differentiation towards both the ductal and the secretory portion of the eccrine gland.

Ancillary