Methotrexate-responsive chronic idiopathic urticaria: a report of two cases


J.E.Gach, Department of Dermatology, Walsgrave Hospitals NHS Trust, Clifford Bridge Road, Walsgrave, Coventry CV2 2DX, U.K. E-mail:


Chronic idiopathic urticaria (CIU) may be severe and refractory to standard therapies. We describe two patients with CIU, neither of whom had detectable autoantibodies, in whom control of the disease was achieved with methotrexate.