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  • 1
    Avraham, H., Vannier, E., Cowley, S., Jiang, S.X., Chi, S., Dinarello, C.A., Zsebo, K.M., Groopman, J.E. (1992) Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood, 79, 365 371.
  • 2
    Banu, N., Wang, J.F., Deng, B., Groopman, J.E., Avraham, H. (1995) Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand. Blood, 86, 1331 1338.
  • 3
    Bartley, T.D., Bogenberger, J., Hunt, P., Li, Y.S., Lu, H.S., Martin, F., Chang, M.S., Samal, B., Nichol, J.L., Swift, S., Johnson, M.J., Hsu, R.J., Parker, V.P., Suggs, S., Skrine, J.D., Merewether, L.A., Clogston, C., Hsu, E., Hokom, H.M., Hornkohl, A., Choi, E., Pangelinan, M., Sun, Y., Mar, V., McNinh, J., Simonet, L., Jacobsen, F., Xie, C., Shutter, J., Chute, H., Basu, R., Selander, L., Trollinger, D., Sieu, L., Padilla, D., Trail, G., Elliott, G., Izumi, R., Covey, T., Crouse, J., Garcia, A., Xu, W., Del Castillo, J., Biron, J., Cole, S., Hu, M.C.T., Pacifici, R., Ponting, I., Saris, C., Wen, D., Yung, Y.P., Lin, H., Bosselman, R.A. (1994) Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl. Cell, 77, 1117 1124.
  • 4
    Bradshaw, D., Hill, C.H., Nixon, J.S., Wilkinson, S.E. (1993) Therapeutic potential of protein kinase C inhibitors. Agents and Actions, 38, 135 147.
  • 5
    Broudy, V.C., Kovach, N.L., Bennett, L.G., Lin, N., Jacobsen, F.W., Kidd, P.G. (1994) Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor. Blood, 83, 2145 2152.
  • 6
    Broudy, V.C., Nakamoto, B., Lin, N., Papayannopoulou, T. (1990) Dynamics of erythropoietin receptor expression on erythropoietin-responsive murine cell lines. Blood, 75, 1622 1626.
  • 7
    Brown, M.S., Anderson, R.G., Goldstein, J.L. (1983) Recycling receptors: the round-trip itinerary of migrant membrane proteins. Cell, 32, 663 667.
  • 8
    Carpentier, J.L., Gordon, P., Robert, A., Orci, L. (1987) Internalization of polypeptide hormones and receptor recycling. Experientia, 53, 47 65.
  • 9
    Catt, K.J., Harwood, J.P., Aguilera, G., Dufau, M.L. (1979) Hormonal regulation of peptide receptors and target cell responses. Nature, 280, 109 116.
  • 10
    Choi, E.S., Nichol, J.L., Hokom, M.M., Hornkohl, A.C., Hunt, P. (1995) Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional. Blood, 85, 402 413.
  • 11
    De Sauvage, F.J., Carver-Moore, K., Luoh, S.M., Ryan, A., Dowd, M., Eaton, D.L., Moore, M.W. (1996) Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. Journal of Experimental Medicine, 183, 651 656.
  • 12
    De Sauvage, F.J., Hass, P.E., Spencer, S.D., Malloy, B.E., Gurney, A.L., Spencer, S.A., Darbonne, W.C., Henzel, W.J., Wong, S.C., Kuang, W.J., Oles, K.J., Hultgren, B., Solbert, L.A., Jr , Goeddel, D.V., Eaton, D.L. (1994) Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature, 369, 533 538.
  • 13
    Emmons, R.V., Reid, D.M., Cohen, R.L., Meng, G., Young, N.S., Dunbar, C.E., Shulman, N.R. (1996) Human thrombopoietin levels are high when thrombocytopenia is due to megakaryocyte deficiency and low when due to increased platelet destruction. Blood, 87, 4068 4071.
  • 14
    Fielder, P., Hass, P., Nagle, M., Stefanich, E., Widmer, R., Keller, G., Eaton, D. (1995) Human platelets as a model for binding, internalization and degradation of thrombopoietin (TPO). Blood Supplement, 1450.
  • 15
    Fielder, P.J., Gurney, A.L., Stefanich, E., Marian, M., Moore, M.W., Carver-Moore, K., De Sauvage, F.J. (1996) Regulation of thrombopoietin levels by c-mpl-mediated binding to platelets. Blood, 87, 2154 2161.
  • 16
    Fuse, A., Kakuda, H., Shima, Y., Van Damme, J., Billiau, A., Sato, T. (1991) Interleukin 6, a possible autocrine growth and differentiation factor for the human megakaryocytic cell line, CMK. British Journal of Haematology, 77, 32 36.
  • 17
    Gordon, M.S. & Hoffman, R. (1992) Growth factors affecting human thrombocytopoiesis: potential agents for the treatment of thrombocytopenia. Blood, 80, 302 307.
  • 18
    Gurney, A.L., Carver-Moore, K., De Sauvage, F.J., Moore, M.W. (1994) Thrombocytopenia in c-mpl-deficient mice. Science, 265, 1445 1447.
  • 19
    Gurney, A.L., Wong, S.C., Henzel, W.J., De Sauvage, F.J. (1995) Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 92, 5292 5296.
  • 20
    Hoffman, R. (1989) Regulation of megakaryocytopoiesis. Blood, 74, 1196 1212.
  • 21
    Jakeman, L.B., Winer, J., Bennett, G.L., Altar, C.A., Ferrara, N. (1992) Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. Journal of Clinical Investigation, 89, 244 253.
  • 22
    Kato, T., Ogami, K., Shimada, Y., Iwamatsu, A., Sohma, Y., Akahori, H., Hoprie, K., Kokubo, A., Kudo, Y., Maeda, E., Kobayashi, K., Ohashi, H., Ozawa, T., Inoue, H., Kawamura, K., Miyazaki, H. (1995) Purification and characterization of thrombopoietin. Journal of Biochemistry, 118, 229 236.
  • 23
    Kaushansky, K., Lok, S., Holly, R.D., Broudy, V.C., Lin, N., Bailey, M.C., Forstrom, J.W., Buddle, M.M., Oort, P.J., Hagen, F.S., Roth, G.J., Papayannopoulou, T., Foster, D.C. (1994) Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin. Nature, 369, 568 571.
  • 24
    Komatsu, N., Suda, T., Moroi, M., Tokuyama, N., Sakata, Y., Okada, M., Nishida, T., Hirai, Y., Sato, T., Fuse, A., Miura, Y. (1989) Growth and differentiation of a human megakaryoblastic cell line, CMK. Blood, 74, 42 48.
  • 25
    Kuter, D.J. (1997) In vivo effects of Mpl ligand administration and emerging clinical applications for the Mpl ligands. Current Opinion in Hematology, 4, 163 170.
  • 26
    Kuter, D.J. & Rosenberg, R.D. (1995) The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood, 85, 2720 2730.
  • 27
    Lok, S., Kaushansky, K., Holly, R.D., Kuijper, J.L., Lofton-Day, C.E., Oort, P.J., Grant, F.J., Heipel, M.D., Burkhead, S.K., Kramer, J.M., Bell, L.A., Sprecher, C.A., Blumberg, H., Johnson, R., Prunkard, D., Ching, A.F.T., Mathewes, S.L., Bailey, M.C., Forstrom, J.W., Buddle, M.M., Osborn, S.G., Evans, S.J., Sheppard, P.O., Presnell, S.R., O'Hara, P.J., Hagen, F.S., Roth, G.J., Foster, D.C. (1994) Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature, 369, 565 568.
  • 28
    McCarty, J.M., Sprugel, K.H., Fox, N.E., Sabath, D.E., Kaushansky, K. (1995) Murine thrombopoietin mRNA levels are modulated by platelet count. Blood, 86, 3668 3675.
  • 29
    Methia, N., Louache, F., Vainchenker, W., Wendling, F. (1993) Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis. Blood, 82, 1395 1401.
  • 30
    Nicola, N.A. (1987) Why do hemopoietic growth factor receptors interact with each other? Immunology Today, 8, 134 140.
  • 31
    Sato, T., Fuse, A., Eguchi, M., Hayashi, Y., Ryo, R., Adachi, M., Kishimoto, Y., Teramura, M., Mizoguchi, H., Shima, Y., Komori, I., Sunami, S., Okimoto, Y., Nakajima, H. (1989) Establishment of a human leukaemic cell line (CMK) with megakaryocytic characteristics from a Down's syndrome patient with acute megakaryoblastic leukaemia. British Journal of Haematology, 72, 184 190.
  • 32
    Schonhorn, J.E., Akompong, T., Wessling-Resnick, M. (1995) Mechanism of transferrin receptor down-regulation in K562 cells in response to protein kinase C activation. Journal of Biological Chemistry, 270, 3698 3705.
  • 33
    Souyri, M., Vigon, I., Penciolelli, J.F., Heard, J.M., Tambourin, P., Wendling, F. (1990) A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors. Cell, 63, 1137 1147.
  • 34
    Sungaran, R., Markovic, B., Chong, B.H. (1997) Localization and regulation of thrombopoietin mRNA expression in human kidney, liver, bone marrow, and spleen using in situ hybridization. Blood, 89, 101 107.
  • 35
    Vigon, I., Mornon, J.P., Cocault, L., Mitjavila, M.T., Tambourin, P., Gisselbrecht, S., Souyri, M. (1992) Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily. Proceedings of the National Academy of Sciences of the United States of America, 89, 5640 5644.
  • 36
    Wendling, F., Maraskovsky, E., Debili, N., Florindo, C., Teepe, M., Titeux, M., Methia, N., Breton-Gorius, J., Cosman, D., Vainchenker, W. (1994) cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature, 369, 571 574.
  • 37
    Yee, N.S., Hsiau, C.W., Serve, H., Vosseller, K., Besmer, P. (1994) Mechanism of down-regulation of c-kit receptor: roles of receptor tyrosine kinase, phosphatidylinositol 3′-kinase, and protein kinase C. Journal of Biological Chemistry, 269, 31991 31998.
  • 38
    Yee, N.S., Langen, H., Besmer, P. (1993) Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells. Journal of Biological Chemistry, 268, 14189 14201.