• 1
    Arriaga, M., South, K., Cohen, J.L., Mazer, E.M. (1987) Interrelationship between mitosis and endomitosis in cultures on human megakaryocyte progenitor cells. Blood, 69, 486 492.
  • 2
    Borgne, A. & Meijer, L. (1996) Sequential dephosphorylation of P34cdc2 on Thr-14 and Tyr-15 at the prophase/metaphase transition. Journal of Biological Chemistry, 271, 27847 27854.
  • 3
    Garcia, P. & Cales, C. (1996) Endoreplication in megakaryoblastic cell lines is accompanied by sustained expression of G1/S cyclins and downregulation if cdc25C. Oncogene, 13, 695 703.
  • 4
    Greenberg, S.M., Rosenthal, D.S., Greeley, T.A., Tantravaki, R., Handin, R.I. (1988) Characterization of a new megakaryocytic cell line: the Dami cell. Blood, 72, 1968 1977.
  • 5
    Hayles, J., Fisher, D., Woollard, A., Nurse, P. (1994) Temporal order of S phase and mitosis in fission yeast is determined by the P34 cdc2-mitotic B cyclin complex. Cell, 78, 813 822.
  • 6
    Kase, H., Iwahashi, K., Matsuda, Y. (1986) K-252a, a potent inhibitor of protein kinase C from microbial origin. Journal of Antibiotics, 39, 1059 1065.
  • 7
    Kase, H., Iwahashi, K., Nakanishi, S., Matsuda, Y., Yamada, K., Takahashi, M., Murata, C., Sato, A., Kaneko, M. (1987) K-252a compounds, novel and potent inhibitor of protein kinase C and cyclic nucleotide-dependent protein kinase. Biochemical and Biophysical Research Communications, 142, 436 440.
  • 8
    Levine, R.F., Hazzard, K.C., Lamberg, J.D. (1982) The significance of megakaryocyte size. Blood, 60, 1122 1131.
  • 9
    Long, M.W., Heffner, C.H., Williams, J.L., Peters, C., Prochownik, E.V. (1990) Regulation of megakaryocytic phenotype in human erythroleukemia cells. Journal of Clinical Investigation, 85, 1072 1084.
  • 10
    Long, M.W., Williams, N., Ebbe, S. (1982) Immature megakaryocytes in the mouse: physical characteristics, cell cycle status and in vitro responsiveness to thrombopoietic stimulating factor. Blood, 59, 569 575.
  • 11
    Moreno, S. & Nurse, P. (1994) Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene. Nature, 367, 236 242.
  • 12
    Murata, T., Hotta, T., Tsushita, K., Suzuki, M., Yoshida, T., Saga, S., Saito, H., Yoshida, S. (1991) Aphidicolin, an inhibitor of DNA replication, blocks the TPA-induced differentiation of a human megakaryoblastic cell line, MEG-01. Blood, 78, 3168 3177.
  • 13
    Murata, T., Saga, S., Hotta, T., Asano, H., Ito, T., Kato, K., Tsushita, K., Kinoshita, T., Ichikawa, A., Yoshida, S., Saito, H. (1993) The close relationship between DNA replication and the selection of differentiation lineages of human erythroleukaemia cell line K562, HEL, and TF1 into either erythroid or megakaryocytic lineages. Experimental Cell Research, 208, 35 43.
  • 14
    Nagasawa, T., Nakazawa, M., Abe, T. (1985) Proliferation and maturation of murine megakaryocyte progenitor cells in a liquid culture system. Experimental Hematology, 13, 51 58.
  • 15
    Nagata, Y., Muro, Y., Todokoro, K. (1997) Thrombopoietin-induced Polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis. Journal of Cell Biology, 139, 449 457.
  • 16
    Ogura, M., Morishima, Y., Okumura, M., Hotta, T., Takamoto, S., Ohno, R., Hirabayashi, M., Nagura, H., Saito, H. (1988) Functional and morphological differentiation of a human megakaryoblastic leukemia cell line (MEG-01) by phorbol diesters. Blood, 72, 49 60.
  • 17
    Rabelleno, E.M., Nachman, R.L., Williams, N., Winchester, R.J., Ross, G.D. (1979) Human megakaryocytes. Journal of Experimental Medicine, 149, 1273 1287.
  • 18
    Straneva, J.E., Goheen, M.P., Hui, S.L., Bruno, E., Hoffman, R. (1986) Terminal cytoplasmic maturation of human megakaryocytes in vitro. Experimental Hematology, 14, 919 929.
  • 19
    Taoka, T., Tokuda, M., Tasaka, T., Hatase, O., Irino, S., Norman, A.W. (1990) Induction of differentiation of HL-60 cells by protein kinase C inhibitor, K252a. Biochemical and Biophysical Research Communications, 170, 1151 1156.
  • 20
    Usui, T., Yoshida, M., Abe, K., Osada, H., Isono, K., Beppu, T. (1991) Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a. Journal of Cell Biology, 115, 1275 1282.
  • 21
    Yoshino, T., Sakaguchi, M., Masuda, T., Kawakita, M. (1996) Two regulation points for differentiation in the cell cycle of human megakaryocytes. British Journal of Haematology, 92, 780 787.