• 1
    Chang, M.S., McNinch, J., Basu, R., Shutter, J., Hsu, R.Y., Perkins, C., Mar, V., Suggs, S., Welcher, A., Li, L., Lu, H., Bartley, T., Hunt, P., Martin, F., Samal, B. & Bogenberger, J. (1995) Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene. Journal of Biological Chemistry, 270, 511514.DOI: 10.1074/jbc.270.2.511
  • 2
    Eaton, D.L. & De Sauvage, F.J. (1997) Thrombopoietin: the primary regulator of megakaryocytopoiesis and thrombopoiesis. Experimental Hematology, 25, 17.
  • 3
    Eyster, M.E., Saletan, S.L., Rabellino, E.M., Karanas, A., McDonald, T.P., Locke, L.A. & Luderer, J.R. (1986) Familial essential thrombocythemia. American Journal of Medicine, 80, 497502.DOI: 10.1016/0002-9343(86)90727-8
  • 4
    Fernandez-Robles, E., Vermylen, C., Martiat, P., Ninane, J. & Cornu, G. (1990) Familial essential thrombocythemia. Pediatric Hematology and Oncology, 7, 373376.
  • 5
    Fickers, M. & Speck, B. (1974) Thrombocythaemia: familial occurrence and transition into blastic crisis. Acta Haematologica, 51, 257265.
  • 6
    Ghilardi, N. & Skoda, R.C. (1999) A single-base deletion in the thrombopoietin (TPO) gene causes familial essential thrombocytosis through a mechanism of more efficient translation of TPO mRNA. (Letter). Blood, 94, 14801482.
  • 7
    Ghilardi, N., Wiestner, A. & Skoda, R.C. (1998) Thrombopoietin production is inhibited by a translational mechanism. Blood, 92, 40234030.
  • 8
    Jorgensen, M.J., Raskind, W.H., Wolff, J.F., Bachrach, H.R. & Kaushansky, K. (1998) Familial thrombocytosis associated with overproduction of thrombopoietin due to a novel splice donor site mutation. (Abstract). Blood, 92, (Suppl. 1), 205a.
  • 9
    Kaushansky, K. (1998) Thrombopoietin. New England Journal of Medicine, 339, 746754.DOI: 10.1056/NEJM199809103391107
  • 10
    Kikuchi, M., Tayama, T., Hayakawa, H., Takahashi, I., Hoshino, H. & Ohsaka, A. (1995) Familial thrombocytosis. British Journal of Haematology, 89, 900902.
  • 11
    Kondo, T., Okabe, M., Sanada, M., Kurosawa, M., Suzuki, S., Kobayashi, M., Hosokawa, M. & Asaka, M. (1998) Familial essential thrombocythemia associated with one-base deletion in the 5′-untranslated region of the thrombopoietin gene. Blood, 92, 10911096.
  • 12
    Kunishima, S., Mizuno, S., Naoe, T., Saito, H. & Kamiya, T. (1998) Genes for thrombopoietin and c-mpl are not responsible for familial thrombocythaemia: a case study. British Journal of Haematology, 100, 383386.DOI: 10.1046/j.1365-2141.1998.00571.x
  • 13
    Luukkonen, B.G., Tan, W. & Schwartz, S. (1995) Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance. Journal of Virology, 69, 40864094.
  • 14
    Murphy, S., Peterson, P., Iland, H. & Laszlo, J. (1997) Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment. Seminars in Hematology, 34, 2939.
  • 15
    Perez-Encinas, M., Bello, J.L., So, P.-C., De Miguel, R. & Tome, S. (1994) Familial myeloproliferative syndrome. American Journal of Hematology, 46, 225229.
  • 16
    Schlemper, R.J., Van Der Maas, A.P.C. & Eikenboom, J.C.J. (1994) Familial essential thrombocythemia: clinical characteristics of 11 cases in one family. Annals of Hematology, 68, 153158.
  • 17
    Slee, P.H.T.J., Van Everdingen, J.J.E., Geraedts, J.P.M., Te Velde, J. & Den Ottolander, G.J. (1981) Familial myeloproliferative disease. Acta Medica Scandinavica, 210, 321327.
  • 18
    Stoffel, R., Wiestner, A. & Skoda, R.C. (1996) Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets. Blood, 87, 567573.
  • 19
    Tahara, T., Usuki, K., Sato, H., Ohashi, H., Morita, H., Tsumura, H., Matsumoto, A., Miyazaki, H., Urabe, A. & Kato, T. (1996) A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders. British Journal of Haematology, 93, 783788.DOI: 10.1046/j.1365-2141.1996.d01-1741.x
  • 20
    Ulibarrena, C., Vecino, A.M., Odriozola, J. & Cesar, J.M. (1997) Familial essential thrombocythemia associated with von Willebrand disease. (Letter). Medica Clinica (Barcelona), 109, 237.
  • 21
    Wiestner, A., Schlemper, R.J., Van Der Maas, A.P. & Skoda, R.C. (1998) An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nature Genetics, 18, 4952.DOI: 10.1038/ng0198-49
  • 22
    Williams, E.C. & Shahidi, N.T. (1991) Benign familial thrombocytosis. American Journal of Hematology, 37, 124125.
  • 23
    Yagisawa, M., Kamizaki, K., Nagase, T., Toba, K., Oouchi, M., Fukuchi, Y., Orishige, H., Hino, M. & Miyazono, K. (1990) Familial essential thrombocythaemia in a daughter and mother. [Japanese]. Nippon Naika Gakkai Zasshi: Journal of the Japanese Society of Internal Medicine, 79, 531532.