• Born, G.V.R. (1962) Aggregation of blood platelets by ADP and its reversal. Nature, 194, 927929.
  • Charo, I.F., Feinman, R.J. & Detwiler, T.C. (1977) Interrelations of platelet aggregation and secretion. Journal of Clinical Investigations, 60, 866873.
  • Fuse, I. (1996) Disorders of platelet function. Critical Reviews in Oncology and Hematology, 22, 125.
  • Fuse, I., Hattori, A., Higashihara, M., Takizawa, S., Takeshige, T., Hanano, M., Nagayama, R., Koike, T., Takahashi, H. & Shibata, A. (1986) A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein. Scandinavian Journal of Haematology, 36, 4454.
  • Fuse, I., Mito, M., Hattori, A., Higuchi, W., Shibata, A., Ushikubi, F., Okuma, M. & Yahata, K. (1993) Defective signal transduction induced by thromboxane A2 in a patient with a mild bleeding disorder: impaired phospholipase C activation despite normal phospholipase A2 activation. Blood, 81, 9941000.
  • Fuse, I., Hattori, A., Mito, M., Higuchi, W., Yahata, K., Shibata, A. & Aizawa, Y. (1996) Pathogenetic analysis of five cases with a platelet disorder characterized by the absence of thromboxane A2 (TXA2)-induced platelet aggregation in spite of normal TXA2 binding activity. Thrombosis and Haemostasis, 76, 10801085.
  • Fuse, I., Higuchi, W. & Aizawa, Y. (2000) Pathogenesis of a bleeding disorder characterized by platelet unresponsiveness to thromboxane A2. Seminars in Thrombosis and Haemostasis, 26, 4345.
  • Grynkiewicz, G., Poenie, M. & Tsein, R.Y. (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. Journal of Biological Chemistry, 260, 34403450.
  • Hardisty, R.M., Machin, S.J., Nokes, T.J.C., Ring, T.J. & Smith, S.W. (1983) A new congenital defect of platelet secretion: impaired responsiveness of the platelets to cytoplasmic free calcium. British Journal of Haematology, 53, 543557.
  • Hattori, A., Takahashi, H., Takahashi, M., Shibata, A. & Okuma, M. (1981) A new familial defect of platelet release mechanism (the intracellular Ca2+ transport defect?). Acta Haematologica Japan, 44, 969972.
  • Higuchi, W., Fuse, I., Hattori, A. & Aizawa, Y. (1999) Mutations of the platelet thromboxane A2 (TXA2) receptor in patients characterized by the absence of TXA2-induced platelet aggregation despite normal TXA2 binding activity. Thrombosis and Haemostasis, 82, 15281531.
  • Hirata, T., Kakizuka, A., Ushikubi, F., Fuse, I., Okuma, M. & Narumiya, S. (1994) Arg60 to Leu mutation of the human thromboxane A2 receptor in a dominantly inherited bleeding disorder. Journal of Clinical Investigations, 94, 16621667.
  • Holmsen, H. & Dangelmaier, C.A. (1981) Evidence that the platelet plasma membrane is impermeable to calcium and magnesium complexes of A23187: A23187-induced secretion is inhibited by Mg2+ and Ca2+, and requires aggregation and active cyclo-oxygenase. Journal of Biological Chemistry, 256, 1044910452.
  • Holmsen, H., Storm, E. & Day, H.J. (1972) Determination of ATP and ADP in blood platelets: a modification of the firefly luciferase assay for plasma. Analytical Biochemistry, 46, 489501.
  • Katsura, M., Miyamoto, N., Hamanaka, N., Kondo, K., Terada, Y., Ohgaki, Y., Kawasaki, A. & Tsuboshima, M. (1983) In vitro and in vivo effects of new powerful thromboxane antagonists (3-alkylamino pinane derivatives). In: Advances in Prostaglandin, Thromboxane and Leukotriene Research (ed. by B.Samuelsson, R.Paoletti & P. Ramwell), pp. 351357. Raven Press, New York.
  • Machin, S.J., Keenan, J.P. & McVerry, B.A. (1983) Defective platelet aggregation to the calcium ionophore A23187 in a patient with a lifelong bleeding disorder. Journal of Clinical Pathology, 36, 11401144.
  • Nakashima, S., Suganuma, A., Matsui, A. & Nozawa, Y. (1991) Thrombin induces a biphasic 1,2-diacylglycerol production in human platelets. Biochemistry Journal, 275, 355361.
  • Palmer, S., Hughes, K.T., Lee, D.Y. & Wakelam, M.J. (1989) Development of a novel, Ins (1,4,5) P3-specific binding assay. Its use to determine the intracellular concentration of Ins (1, 4,5) P3 in unstimulated and vasopressin–stimulated rat hepatocytes. Cellular Signalling, 1, 147156.
  • Poll, C. & Westwick, J. (1986) Phorbol esters modulate thrombin-operated calcium mobilisation and dense granule release in human platelets. Biochemica Biophysics Acta, 886, 434440.
  • Rao, A.K., Kowalska, M.A. & Disa, J. (1989) Impaired cytoplasmic ionized calcium mobilization in inherited platelet secretion defects. Blood, 74, 664672.
  • Rittenhouse, S.E. (1984) Activation of human platelet phospholipase C by ionophore A23187 is totally dependent upon cyclo-oxygenase products and ADP. Biochemical Journal, 222, 103110.
  • Searcy, G.P., Frojmovic, M.M., McNicol, A., Robertson, C., Wong, T. & Gerrard, J.M. (1994) Platelets from bleeding Simmental cattle mobilize calcium, phosphorylate myosin light chain and bind normal numbers of fibrinogen molecules but have abnormal cytoskeletal assembly and aggregation in response to ADP. Thrombosis and Haemostasis, 71, 240246.