You have full text access to this OnlineOpen article

Allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning: results of a prospective multicentre study

  1. Rodrigo Martino1,
  2. María Dolores Caballero2,
  3. Carmen Canals1,
  4. José Antonio Pérez Simón2,
  5. Carlos Solano3,
  6. Alvaro Urbano-Ispízua4,
  7. Joan Bargay5,
  8. Consolación Rayón6,
  9. Antonio Léon7,
  10. Josep Sarrá8,
  11. Jesús Odriozola9,
  12. Javier García Conde3,
  13. Jorge Sierra1,
  14. Jesús San Miguel2,
  15. for the ALLOPBSCT subcommittee of the Spanish Group for Haematopoietic Transplantation (GETH) and the Group GEL-TAMO1

Article first published online: 20 DEC 2001

DOI: 10.1046/j.1365-2141.2001.03153.x

Issue

British Journal of Haematology

British Journal of Haematology

Volume 115, Issue 3, pages 653–659, December 2001

Additional Information

How to Cite

Martino, R., Caballero, M. D., Canals, C., Simón, J. A. P., Solano, C., Urbano-Ispízua, A., Bargay, J., Rayón, C., Léon, A., Sarrá, J., Odriozola, J., Conde, J. G., Sierra, J., San Miguel, J. and for the ALLOPBSCT subcommittee of the Spanish Group for Haematopoietic Transplantation (GETH) and the Group GEL-TAMO (2001), Allogeneic peripheral blood stem cell transplantation with reduced-intensity conditioning: results of a prospective multicentre study. British Journal of Haematology, 115: 653–659. doi: 10.1046/j.1365-2141.2001.03153.x

Author Information

  1. 1

    Servicio de Hematología Clínica, Hospital de la Santa Creu i Sant Pau, Barcelona,

  2. 2

    Servicio de Hematología, Hospital Universitario de Salamanca,

  3. 3

    Servicio de Hematología, Hospital Clínico y Universitario de Valencia,

  4. 4

    Servicio de Hematología, Hospital Clínico y Provincial de Barcelona,

  5. 5

    Servicio de Hematología, Hospital de Son Dureta, Palma de Mallorca,

  6. 6

    Servicio de Hematología, Hospital de Covadonga, Oviedo,

  7. 7

    Hospital SAS de Jerez de la Frontera,

  8. 8

    Institut Catalá d'Oncologia, l'Hospitalet de Llobregat, and

  9. 9

    Hospital Ramón y cajal, Madrid, Spain

* Dr R. Martino, Servei d'Hematologia Clínica, Hospital de la Santa Creu i Sant Pau, Avenue Sant Antoni Ma Claret, 167, 08025 Barcelona, Spain. E-mail: rmartino@hsp. santpau.es

Publication History

  1. Issue published online: 20 DEC 2001
  2. Article first published online: 20 DEC 2001
  3. Received 17 April 2001; accepted for publication 18 July 2001

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (109K)

References

  • Anonymous (2000) Report on the state of the art in blood and marrow transplantation-the IBMTR/ABMTR summary slides with guide. IBMTR/ABMTR Newsletter, 7, 3–10.
  • Carella, A.M., Giralt, S., Slavin, S. (2000a) Nonmyeloablative therapy with allogeneic hematopoietic stem cell transplantation as treatment of haematologicalal neoplasia. Haematologica, 85, 304–313.
  • Carella, A.M., Champlin, R., Slavin, S., McSweeney, P., Storb, R. (2000b) Mini-allografts: ongoing trials in humans. Bone Marrow Transplantation, 25, 345–350.
  • Champlin, R.E., Schmitz, N., Horowitz, M.M., Chapuis, B., Chopra, R., Cornelissen, J.J., Gale, R.P., Goldman, J.M., Loberiza, F.R., Hertenstein, B., Klein, J.P., Montserrat, E., Zhang, M.J., Ringdén, O., Tomany, S.C., Rowlings, P.A., Van Hoef, M.E.H.M., Gratwohl, A. (2000) Blood stem cells compared with bone marrow as a source of hematopoietic cells for allogeneic transplantation. Blood, 95, 3702–3709.
  • Childs, R., Clave, E., Contentin, N., Jayasekera, D., Hensel, N., Leitman, S., Read, E.J., Carter, C., Bahceci, E., Young, N.S., Barrett, A.J. (1999) Engraftment kinetics after nonmyeloablative allogeneic peripheral blood stem cell transplantation: full donor T-cell chimerism precedes alloimmune responses. Blood, 94, 3234–3241.
  • Collins, Jr, R.H., Shpilberg, O., Drobyski, W.R., Porter, D.L., Giralt, S., Champlin, R., Goodman, S.A., Wolff, S.N., Hu, W., Verfaillie, C., List, A., Dalton, W., Ognoskie, N., Chetrit, A., Antin, J.H., Nemunaitis, J. (1997) Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. Journal of Clinical Oncology, 15, 433–444.
  • Entrala, C., Lorente, M., Lorente, J.A. (1998) Fluorescent multiplex analysis of nine STR loci: Spanish population data. Forensic Science International, 98, 179–183.DOI: 10.1016/s0379-0738(98)00165-0
  • Ferrara, J.L.M. & Deeg, H.J. (1991) Graft-versus-host disease. New England Journal of Medicine, 324, 667–674.
  • Giralt, S., Estey, E., Albitar, M., Van Besien, K., Rondon, G., Anderlini, P., O'Brien, S., Khouri, I., Gajewski, J., Mehra, R., Claxton, D., Andersson, B., Beran, M., Przepiorka, D., Koller, C., Kornblau, S., Korbling, M., Keating, M., Kantarjian, H., Champlin, R., Korbling, M. (1997) Engraftment of allogeneic haematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy. Blood, 89, 4531–4536.
  • Giralt, S., Thall, P.F., Khouri, I., Wang, X., Braunschweig, I., Ippolitti, C., Claxton, D., Donato, M., Brutton, J., Cohen, A., Davis, M., Andersson, B., Anderlini, P., Gajewski, J., Kornblau, S., Andreeff, M., Przepiorka, D., Ueno, N.T., Molldrem, J., Champlin, R. (2001) Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with haematological malignancies undergoing allogeneic progenitor cell transplantation. Blood, 97, 631–637.
  • Horowitz, M.M., Gale, R.P., Sondel, P.M., Goldman, J.M., Kersey, J., Kolb, H.J., Rimm, A.A., Ringden, O., Rozman, C., Speck, B., Truitt, R.L., Zwaan, F.E., Bortin, M.M. (1990) Graft-versus-leukemia reactions after bone marrow transplantation. Blood, 75, 555–562.
  • Khouri, I.F., Keating, M., Przepiorka, D., Anderlini, P.O., Brien, S., Giralt, S., Ippoliti, C., Von Wolff, B., Gajewski, J., Donato, M., Claxton, D., Ueno, N., Andersson, B., Gee, A., Champlin, R. (1998) Transplant lite: Induction of graft-versus-malignancy using fludarabine-based non-ablative chemotherapy and allogeneic blood progenitor cell transplantation as treatment for lymphoid malignancy. Journal of Clinical Oncology, 8, 2817–2824.
  • Kolb, H., Schattenberg, A., Goldman, J., Hertenstein, B., Jacobsen, N., Arcese, W., Ljungman, P., Ferrant, A., Verdonck, L., Niederwieser, D. (1995) Graft-versus-leukaemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia. Blood, 86, 2041–2050.
  • Kottaridis, P.D., Milligan, D.W., Chopra, R., Chakraverty, R.K., Chakrabarti, S., Robinson, S., Peggs, K., Verfuerth, S., Pettengell, R., Marsh, J.C.W., Schey, S., Mahendra, P., Morgan, G.J., Hale, G., Waldmann, H., Ruiz de Elvira, M.C., Williams, C.D., Devereux, S., Linch, D.C., Goldstone, A.H., Mackinnon, S. (2000) In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation. Blood, 96, 2419–2425.
  • Kupferschmid, T.D., Calicchio, T., Budowle, B. (1999) Maine Caucasian population DNA database using twelve short tandem repeat loci. Journal of Forensic Science, 44, 392–339.
  • McSweeney, P., Niederwieser, D., Shizuru, J., Molina, A., Wagner, J., Minor, S., Radich, J., Chauncey, T., Hegenbart, U., Maloney, D., Nash, R., Sandmaier, B., Blume, K., Storb, R. (1999) Outpatient allografting with minimally myelosuppressive, immunosuppressive conditioning of low-dose TBI and postgrafting cyclosporine and mycophenolate mofetil. Blood, 94, 393a.
  • Miller, A.B., Hoogstraten, B., Staquet, M., Winkler, A. (1981) Reporting results of cancer treatment. Cancer, 47, 207–214.
    Direct Link:
  • Przepiorka, D., Weisdorf, D., Martin, P., Klingemann, H.G., Beatty, P., Hows, J., Thomas, E.D. (1995) 1994 Consensus Conference on Acute GVHD Grading. Bone Marrow Transplantation, 15, 825–830.
  • Radich, J.P., Gooley, T., Sanders, J.E., Anasetti, C., Chauncey, T., Appelbaum, F.R. (2000) Second allogeneic transplantation after failure of first autologous transplantation. Biology of Blood and Marrow Transplantation, 6, 272–279.
  • Slavin, S., Nagler, A., Naparstek, E., Kapelushnik, Y., Aker, M., Cividalli, G., Varadi, G., Kirschbaum, M., Ackerstein, A., Samuel, S., Amar, A., Brautbar, C., Ben-Tal, O., Eldor, A., Or, R. (1998) Non-myeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant haematologic diseases. Blood, 91, 756–763.
View Full Article (HTML) Get PDF (109K)