Overnight deep body temperature and urinary cortisol excretion in infants from economically deprived areas
Version of Record online: 30 OCT 2003
Child: Care, Health and Development
Volume 29, Issue 6, pages 473–480, November 2003
How to Cite
Wailoo, M. P., Westaway, J. A., Joseph, D., Petersen, S. A., Davies, T. and Thompson, J. R. (2003), Overnight deep body temperature and urinary cortisol excretion in infants from economically deprived areas. Child: Care, Health and Development, 29: 473–480. doi: 10.1046/j.1365-2214.2003.00367.x
- Issue online: 30 OCT 2003
- Version of Record online: 30 OCT 2003
- Accepted for publication 23 July 2003
- deprived infants;
- physiological development;
- sleeping body temperature
Objectives To assess the pattern of postnatal physiological maturation in economically deprived infants by measuring the age-related changes in deep body temperature during night-time sleep.
Setting Inner city Leicester, UK.
Participants Forty-eight infants aged 6–21 weeks from economically deprived areas and 87 control infants from more affluent areas.
Outcome measures Average deep body temperature between 2 and 4 h after bedtime, overnight and early morning urinary cortisol excretion.
Results Both groups showed a decline in overnight deep body temperature with age that averaged 0.030°C per week (SE = 0.003). Over the age range studied, the average age-adjusted overnight temperature in the infants from deprived homes was 0.090°C (SE = 0.028) higher than that for the affluent group (P = 0.001). Deprived infants had on average 51% higher overnight urinary cortisol and 80% higher morning cortisol. The differences remained when the effects of room temperature, clothing, smoking, birthweight and gestational age were taken into account.
Conclusion These indicators of postnatal physiological maturation suggest that infants from economically deprived homes mature less quickly. This might increase their vulnerability to illness.