• 1
    Brouet JC, Clauvel P-C, Danon F, Klein M, Seligman M. Biological and clinical significance of cryoglobulins. A report of 86 cases. Am J Med 1974; 57:77588.
  • 2
    Abel G, Zhang Q, Agnello V. Hepatitis C virus infection in type II mixed cryoglobulinemia. Arthritis Rheum 1993; 36:13419.
  • 3
    Weiner SM, Berg T, Berthold H et al. A clinical and virological study of hepatitis C virus-related cryoglobulinemia in Germany. J Hepatol 1998; 29:37584.
  • 4
    Miescher PA, Huang YP, Izui S. Type II cryoglobulinemia. Semin Hematol 1995; 32:805.
  • 5
    Rother U, Rother K, Flad HD, Miescher PA. Bithermic complement activation in cryoglobulinemic serum. Eur J Clin Invest 1972; 2:5965.
  • 6
    Wilson MR, Arroyave CM, Miles L, Tan EM. Immune reactants in cryoproteins. Relationship to complement activation. Ann Rheum Dis 1977; 36:5408.
  • 7
    Morel F, Cholley LC, Dianoux AC et al. Modulation of human neutrophil function by fibronectin degradation products isolated from cryoglobulins. Inflammation 1992; 16:32541.
  • 8
    Fontana A, Grob PJ, Frick P. Die Kryoglobulinämien. Erg Inn Med Kinderheilk 1988; 56:131.
  • 9
    Weiner SM, Röther E, Weber S, Schlesier M, Berthold H, Peter HH. Kältelabile Serum- und Plasmaproteine: klinische und diagnostische Wertigkeit von Kryoglobulinen, Kryofibrinogen und Kälteagglutininen. Immun Infekt 1994; 22:16976.
  • 10
    Baumann H & Gauldie J. The acute phase response. Immunol Today 1994; 15:7480.
  • 11
    Gewurz H, Mold C, Siegel J, Fiedel B. C-reactive protein and the acute phase response. Adv Int Med 1982; 27:34572.
  • 12
    Pepys MB & Baltz ML. Acute phase proteins with special reference to C-reactive protein and related proteins (pentaxins) and serum amyloid A protein. Adv Immunol 1983; 34:141212.
  • 13
    Kilpatrick JM & Volanakis JE. Molecular genetics, structure, and function of C-reactive protein. Immunol Res 1991; 10:4353.
  • 14
    Kaplan MH & Volanakis JE. Interaction of C-reactive protein complexes with the complement system. I. Consumption of human complement associated with the reaction of C-reactive protein with pneumococcal C-polysaccharide and with the choline phosphatides, lecithin and sphingomyelin. J Immunol 1974; 112:213547.
  • 15
    Vaith P, Prasauskas V, Potempa L, Peter HH. Complement activation by C-reactive protein on the HEp-2 cell substrate. Int Arch Allergy Immunol 1996; 111:10717.
  • 16
    Pepys MB, Booth SE, Tennent GA, Butler PJG, Williams DG. Binding of pentraxins to different nuclear structures: C-reactive protein binds to small nuclear ribonucleoprotein particles, serum amyloid P component binds to chromatin and nucleoli. Clin Exp Immunol 1994; 97:1527.
  • 17
    Du Clos TW. C-reactive protein reacts with the small nuclear ribonucleoprotein. J Immunol 1989; 143:25539.
  • 18
    Hurwitz D, Quismorio FP, Friou GJ. Cryoglobulinaemia in patients with infectious endocarditis. Clin Exp Immunol 1975; 15:13141.
  • 19
    Grützmeier S & Von Schenck H. C-reactive protein-immunoglobulin complexes in two patients with macroglobulinemia. Scand J Clin Lab Invest 1987; 47:81922.
  • 20
    Mayer MM. Complement and complement fixation. In: KabatEA, MayerMM, eds. Experimental immunochemistry, 2nd edn. Springfield, IL: Charles C. Thomas, 1961:133240.
  • 21
    Roether E, Lang B, Coldewey R, Hartung K, Peter HH. Complement split product C3d as an indicator of disease activity in systemic lupus erythematosus. Clin Rheumatol 1993; 12:315.
  • 22
    Musset L, Diemert MC, Taibi F et al. Characterization of cryoglobulins by immunoblotting. Clin Chem 1992; 38:798802.
  • 23
    Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:6805.
  • 24
    Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76:43504.
  • 25
    Highton J & Hessian P. A solid-phase enzyme immunoassay for C-reactive protein: clinical value and the effect of rheumatoid factor. J Immunol Meth 1984; 68:18592.
  • 26
    Potempa LA, Siegel J, Gewurz H. Binding reactivity of C-reactive protein for polycations. II. Modulatory effects of calcium and phosphocholine. J Immunol 1981; 127:150914.
  • 27
    Ziccardi RJ. Spontaneous activation of the first complement component of human complement (C1) by an intramolecular autocatalytic mechanism. J Immunol 1982; 128:25004.
  • 28
    Cheung AK, Parker CJ, Janatova J. Analysis of the complement C3 fragments associated with hemodialysis membranes. Kidney Int 1989; 35:57688.
  • 29
    Gorevic PD, Kassab HJ, Levo Y et al. Mixed cryoglobulinemia: clinical aspects and long-term follow-up of 40 patients. Am J Med 1980; 69:287308.
  • 30
    Weiner SM, Lebrecht D, Peter HH, Vaith P. Immunochemical analysis of cryoglobulins. Immunol Lett 2000; 73:196.
  • 31
    Müller S, Rother U, Westerhausen M. Complement activation by cryoglobulin. Evidence for a pathogenic role of an IgG (kappa) cryoglobulin in cutaneous vasculitis. Clin Exp Immunol 1976; 23:23341.
  • 32
    Maire MA, Barnet M, Carpentier N, Miescher PA, Lambert PH. Identification of components of IC purified from human sera. I. Immune complexes purified from sera of patients with SLE. Clin Exp Immunol 1983; 51:21524.
  • 33
    Croce MV & Segal-Eiras A. Identification of acute-phase proteins (APP) in circulating immune complexes (CIC) in esophageal cancer patients' sera. Cancer Invest 1996; 14:4216.
  • 34
    Smith AJ, Kyle V, Cawston TE, Hazleman BL. Isolation and analysis of immune complexes from sera of patients with polymyalgia rheumatica and giant cell arteritis. Ann Rheum Dis 1987; 46:46874.
  • 35
    Motie M, Brockmeier S, Potempa LA. Binding of model soluble immune complexes to modified C-reactive protein. J Immunol 1996; 156:443541.
  • 36
    Köttgen E, Hell B, Kage A, Tauber R. Lectin specificity and binding characteristics of human C-reactive protein. J Immunol 1992; 149:44553.
  • 37
    Ballou SP & Macintyre SS. Absence of a binding reactivity of human C-reactive protein for immunoglobulin or immune complexes. J Lab Clin Med 1990; 115:3328.
  • 38
    Prasauskas V. Komplementaktivierung durch C-reaktives Protein (in vitro). Immunologische Analysen zur Rolle von neo-CRP und Kryoglobulinen. Doctoral Thesis, University Freiburg, Germany, 1995.
  • 39
    Korngold L. A human monoclonal IgM with binding activity for C-reactive protein (CRP). Clin Immunol Immunopathol 1974; 3:23642.
  • 40
    Ponge TD, Le Carrer DL, Sagniez MM, Pontet M, Cottin SL. False rise in C-reactive protein in a patient with monoclonal IgM immunoglobulin. Clin Chim Acta 1993; 220:1016.
  • 41
    Mold C, Gurule C, Otero D, Du Clos TW. Complement-dependent binding of C-reactive protein complexes to human erythrocyte CR1. Immunol Immunopathol 1996; 2:15360.
  • 42
    Romero IR, Morris C, Rodriguez M, Du Clos TW. Inflammatory potential of C-reactive protein complexes compared to immune complexes. Clin Immunol Immunopathol 1998; 87:15562.DOI: 10.1006/clin.1997.4516
  • 43
    Wolbink GJ, Brouwer MC, Buysmann S, Ten Berge IJM, Hack CE. CRP-mediated activation of complement in vivo. Assessment by measuring circulating complement-C-reactive protein complexes. J Immunol 1996; 157:4739.
  • 44
    Mold C, Kingzette M, Gewurz H. C-reactive protein inhibits pneumococcal activation of the alternative pathway by increasing the interaction between factor H and C3b. J Immunol 1984; 133:8825.
  • 45
    Jarva H, Jokiranta TS, Hellwage J, Zipfel PF, Meri S. Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8–11. J Immunol 1999; 163:395762.