• 1
    Tomokuni A, Aikoh T, Matsuki T et al. Elevated soluble Fas/APO-1 (CD95) levels in silicosis patients without clinical symptoms of autoimmune diseases or malignant tumors. Clin Exp Immunol 1997; 110: 3039.
  • 2
    Medema JP, Scaffidi C, Kischkel FC et al. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J 1997; 16: 2794804.
  • 3
    Fisher GH, Rosenberg FJ, Straus SE et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995; 81: 93545.
  • 4
    Rieuz-Iaucat F, Le Deist F, Hivroz C et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995; 268: 13479.
  • 5
    Frank R. Spot synthesis. an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedron 1992; 48: 921732.DOI: 10.1016/s0040-4020(01)85612-x
  • 6
    Austen BM, Frears ER, Davies H. The use of Seldi ProteinChipTM arrays to monitor production of Alzheimer's β-amyloid in transfected cells. J Peptide Sci 2000; 6: 45969.DOI: 10.1002/1099-1387(200009)6:9<459::aid-psc286>;2-b
  • 7
    Muzio M, Chinnaiyan AM, Kischkel FC et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996; 85: 81727.
  • 8
    Bertin J, Armstrong RC, Ottilie S et al. Death effector domain- containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1- induced apoptosis. Proc Natl Acad Sci USA 1997; 94: 11726.
  • 9
    Singh A, Ni J, Aggarwal BB. Death domain receptors and their role in cell demise. J Interferon Cytokine Res 1998; 18: 43950.
  • 10
    Blanchard H, Donepudi M, Tschopp M et al. Caspase-8 specificity probed at subsite S4. Crystal structure of the caspase-8-z-DEVD-cho complex. J Mol Biol 2000; 302: 916.
  • 11
    Blanchard H, Kodandapani L, Mittl PR et al. The three dimensional structure of caspase-8: an initiator enzyme in appotosis. Structure 1999; 7: 112533.
  • 12
    Thornberry NA, Miller DK, Nicholson DW. Interleukin-1-β- converting enzyme and related proteases as potential targets in inflammation and apoptosis. Perspective Drug Discovery Design 1994; 2: 38999.
  • 13
    Grenet J, Teitz T, Wei T et al. Structure and chromosome localization of the human CASP8 gene. Gene 1999; 226: 22532.DOI: 10.1016/s0378-1119(98)00565-4
  • 14
    Morrison S. The immune system in health and desease. In: Janeway, CA, Trarers, P, Walport, M, Shomchik, MJ, eds. Immunobiology, 5th edn. New York: Garland Publishing, 2001:131–56.
  • 15
    Lehmann PV, Forsthuber T, Miller A et al. Spreading of T cell autoimmunity to cryptic determinants of an autoantigen. Nature 1992; 358: 1557.
  • 16
    Goebels N, Hofstetter H, Schmidt S et al. Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects. Epitope spreading versus clonal persistence. Brain 2000; 123: 50818.
  • 17
    Arbuckle MR, Reichlin M, Harley JB et al. Shared early autoantibody recognition events in the development of anti-Sm B/B′ in human Lupus. Scad J Immunol 1999; 50: 44755.
  • 18
    Vanderlugt CL, Neville KL, Nikcevich KM et al. Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis. J Immunol 2000; 164: 6708.
  • 19
    Perriard J, Jaunin F, Favre B et al. IgG autoantibodies from bullous pemphigoid (BP) patients bind antigenic sites on both the extracellular and the intracellular domains of the BP antigen 180. J Inves Dermatol 1999; 112: 1417.
  • 20
    McMillan R, Bowditch RD, Tani P et al. A non-thrombocytopenic bleeding disorder due to an IgG4-kappa anti-GPIIb/IIIa autoantibody. Br J Haematol 1996; 95: 7479.
  • 21
    Modre B, Allen J, Wojnarowska F. Does class switching contribute to remissiong in bullous pemphigoid? Acta Derm Venerol 1999; 79: 12731.
  • 22
    Garcia BE, Sanz ML, Gato JJ et al. IgG4 blocking effect on the release of antigen-specific histamine. J Invest Allergol Clin Immunol 1993; 3: 2633.
  • 23
    Hertl M, Veldman C. Pemphigus-paradigm of autoantibody-mediated autoimmunity. Skin Pharmacol Appl Skin Physiol 2001; 14: 40818.