• 1
    Fritzler MJ. Autoantibodies in scleroderma. J Dermatol 1993; 20: 25768.
  • 2
    Pollard KM, Reimer G, Tan EM. Autoantibodies in scleroderma. Clin Exp Rheumatol 1989; 7: S57S62.
  • 3
    Kipnis RJ, Craft J, Hardin JA. The analysis of antinuclear and antinucleolar autoantibodies of scleroderma by radioimmunoprecipitation assays. Arthritis Rheum 1990; 33: 14317.
  • 4
    Fimiani C. Systemic sclerosis: a woman disease. Mod Asp Immunobiol 2001; 1: 2337.
  • 5
    Arnett FC, Reveille JD, Goldstein R et al. Autoantibodies to fibrillarin in systemic sclerosis (scleroderma). An immunogenetic, serologic, and clinical analysis. Arthritis Rheum 1996; 39: 115160.
  • 6
    Tollervey D. Trans-acting factors in ribosome synthesis. Exp Cell Res 1996; 229: 22632.
  • 7
    Tollervey D, Kiss T. Function and synthesis of small nucleolar RNAs. Current Opinion Cell Biol 1997; 9: 33742.
  • 8
    Venema J, Tollervey D. Ribosome synthesis in Saccharomyces cerevisiae. Annu Rev Genet 1999; 33: 261311.
  • 9
    Balakin AG, Smith L, Fournier MJ. The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. Cell 1996; 86: 82334.
  • 10
    Aris JP, Blobel G. cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera. Proc Natl Acad Sci USA 1991; 88: 9315.
  • 11
    Newman DR, Kuhn JF, Shanab GM, Maxwell ES. Box C/D snoRNA-associated proteins: two pairs of evolutionarily ancient proteins and possible links to replication and transcription. RNA 2000; 6: 86179.
  • 12
    Lyman SK, Gerace L, Baserga SJ. Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins. RNA 1999; 5: 1597604.
  • 13
    Ganot P, Caizergues-Ferrer M, Kiss T. The family of Box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes Dev 1997; 11: 94156.
  • 14
    Meier UT, Blobel G. NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria. J Cell Biol 1994; 127: 150514.
  • 15
    Dragon F, Pogacic V, Filipowicz W. In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs. Mol Cell Biol 2000; 20: 303748.
  • 16
    Pogacic V, Dragon F, Filipowicz W. Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10. Mol Cell Biol 2000; 20: 902840.
  • 17
    Gold HA, Craft J, Hardin JA, Bartkiewicz M, Altman S. Antibodies in human serum that precipitate ribonuclease P. Proc Natl Acad Sci USA 1988; 85: 54837.
  • 18
    Gold HA, Topper JN, Clayton DA, Craft J. The RNA processing enzyme RNase MRP is identical to the Th RNP and related to RNase P. Science 1989; 245: 137780.
  • 19
    Bartkiewicz M, Gold H, Altman S. Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells. Genes Dev 1989; 3: 48899.
  • 20
    Van Eenennaam H, Jarrous N, Van Venrooij WJ, Pruijn GJM. Architecture and function of the human endonucleases RNase P and RNase MRP. IUBMB Life 2000; 49: 26572.
  • 21
    Humbel RL. Detection of antinuclear antibodies by immunofluorescence. In: Van VenrooijWJ, MainiRN. Manual of biological markers of disease A2. Dordrecht: Kluwer Academic Publishers, 1993:116.
  • 22
    Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 31524.
  • 23
    Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 12717.
  • 24
    Masi AT. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980; 23: 58190.
  • 25
    Vitali C, Bombardieri S, Moutsopoulos HM et al. Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community. Arthritis Rheum 1993; 36: 3407.
  • 26
    Bohan A, Peter JB. Polymyositis and dermatomyositis (first of two parts). N Engl J Med 1975; 292: 3447.
  • 27
    Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). N Engl J Med 1975; 292: 4037.
  • 28
    Verheijen R, Wiik A, De Jong BA et al. Screening for auto-antibodies to the nucleolar U3- and Th (7–2) ribonucleoproteins in patients’ sera using antisense riboprobes. J Immunol Meth 1994; 169: 17382.
  • 29
    Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. New York: Cold Spring Harbor Laboratory Press 1989.
  • 30
    Brouwer R, Hengstman GJ, Vree Egberts W et al. Autoantibody profiles in the sera of European patients with myositis. Ann Rheum Dis 2001; 60: 11623.
  • 31
    Kasturi KN, Hatakeyama A, Spiera H, Bona CA. Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes. J Exp Med 1995; 181: 102736.
  • 32
    Okano Y, Medsger TAJ. Autoantibody to Th ribonucleoprotein (nucleolar 7–2 RNA protein particle) in patients with systemic sclerosis. Arthritis Rheum 1990; 33: 18228.
  • 33
    Reddy R, Tan EM, Henning D, Nohga K, Busch H. Detection of a nucleolar 7–2 ribonucleoprotein and a cytoplasmic 8–2 ribonucleoprotein with autoantibodies from patients with scleroderma. J Biol Chem 1983; 258: 13836.
  • 34
    Yamane K, Ihn H, Kubo M et al. Antibodies to Th/To ribonucleoprotein in patients with localized scleroderma. Rheumatology 2001; 40: 6836.
  • 35
    Reimer G, Steen VD, Penning CA, Medsger TAJ, Tan EM. Correlates between autoantibodies to nucleolar antigens and clinical features in patients with systemic sclerosis (scleroderma). Arthritis Rheum 1988; 31: 52532.
  • 36
    Okano Y, Steen VD, Medsger TAJ. Autoantibody to U3 nucleolar ribonucleoprotein (fibrillarin) in patients with systemic sclerosis. Arthritis Rheum 1992; 35: 95100.
  • 37
    Fujii T, Mimori T, Akizuki M. Detection of autoantibodies to nucleolar transcription factor NOR 90/hUBF in sera of patients with rheumatic diseases, by recombinant autoantigen-based assays. Arthritis Rheum 1996; 39: 13138.
  • 38
    Pluk H, Soffner J, Lührmann R, Van Venrooij WJ. cDNA cloning and characterization of the human U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein. Mol Cell Biol 1998; 18: 48898.
  • 39
    Lee SJ, Baserga SJ. Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing. Mol Cell Biol 1999; 19: 544152.
  • 40
    Westendorf JM, Konstantinov KN, Wormsley S et al. M phase phosphoprotein 10 is a human U3 small nucleolar ribonucleoprotein component. Mol Biol Cell 1998; 9: 43749.
  • 41
    Tomasevic N, Peculis B. Identification of a U8 snoRNA-specific binding protein. J Biol Chem 1999; 274: 3591420.
  • 42
    Brahms H, Raymackers J, Union A, De Keyser F, Meheus L, Luhrmann R. The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies. J Biol Chem 2000; 275: 171229.
  • 43
    Schellekens GA, De Jong BA, Van Den Hoogen FH, Van De Putte LB, Van Venrooij WJ. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest 1998; 101: 27381.
  • 44
    Reimer G, Raska I, Scheer U, Tan EM. Immunolocalization of 7-2-ribonucleoprotein in the granular component of the nucleolus. Exp Cell Res 1988; 176: 11728.
  • 45
    Yuan Y, Tan E, Reddy R. The 40-kilodalton to autoantigen associates with nucleotides 21–64 of human mitochondrial RNA processing/7-2 RNA in vitro. Mol Cell Biol 1991; 11: 526674.
  • 46
    Li K, Smagula CS, Parsons WJ et al. Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. J Cell Biol 1994; 124: 87182.
  • 47
    Lygerou Z, Pluk H, Van Venrooij WJ, Seraphin B. hPop1: an autoantigenic protein subunit shared by the human RNase P and RNase MRP ribonucleoproteins. EMBO J 1996; 15: 593648.
  • 48
    Eder PS, Kekuda R, Stolc V, Altman S. Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P. Proc Natl Acad Sci USA 1997; 94: 11016.
  • 49
    Maxwell ES, Fournier MJ. The small nucleolar RNAs. Annu Rev Biochem 1995; 64: 897934.
  • 50
    Kiss T. Small nucleolar RNA-guided post-transcriptional modification of cellular RNAs. EMBO J 2001; 20: 361722.