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Bethesda 2001


J. H. F. Smith Consultant Histopathologist and Cytopathologist, Department of Histopathology, E Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK. Tel.: 0114 271 3728; Fax: 0114 271 2200; E-mail:


The Bethesda system (TBS) for reporting cervical/vaginal cytological diagnoses was originally developed in 1988 at a National Cancer Institute (NCI) workshop convened to consider the benefits of increased standardization in the diagnostic reports provided by cytology laboratories.1 It rapidly gained acceptance in laboratory practice in the USA and beyond2,3 and three years later the NCI sponsored another workshop to assess the use of TBS in practice and consider areas for improvement.4 Subsequently an illustrated guide was published.5