Acral myxoinflammatory fibroblastic sarcoma in FNAB samples: can we distinguish it from other myxoid lesions?
Article first published online: 24 APR 2003
Volume 14, Issue 2, pages 73–78, April 2003
How to Cite
Pohar-Marinšek, Ž., Fležar, M. and Lamovec, J. (2003), Acral myxoinflammatory fibroblastic sarcoma in FNAB samples: can we distinguish it from other myxoid lesions?. Cytopathology, 14: 73–78. doi: 10.1046/j.1365-2303.2003.00020.x
- Issue published online: 24 APR 2003
- Article first published online: 24 APR 2003
- Accepted for publication 18 December 2002
- acral myxoinflammatory fibroblastic sarcoma;
- myxoid tumours;
- fine needle aspiration biopsy
We analysed cytomorphological characteristics of three fine needle aspiration biopsy (FNAB) samples of acral myxoinflammatory fibroblastic sarcoma (AMIFS) as well as the features of a number of other benign and malignant myxoid lesions. The analysis showed that FNAB samples from two cases of AMIFS had similar cytomorphology, containing all the characteristic features described in surgical biopsies: myxoid material, spindle cells with bipolar cytoplasmic extensions, epithelioid cells with globules of extra-cellular material, ganglion-like and lipoblast-like giant cells. Only the inflammatory component was scarce. The third sample did not contain features typical of AMIFS. Samples from other myxoid tumours resembled AMIFS to some extent, however, none of them contained all three tumour components characteristic of AMIFS. Cytomorphology of AMIFS may be characteristic enough to enable a definitive diagnosis from FNAB, provided all the distinctive features are sampled.