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Keywords:

  • islet cell tumour;
  • clear cell;
  • immunohistochemistry;
  • electron microscopy

Aims: A previously unreported clear cell variant of islet cell tumour of the pancreas is described. Methods and results: By light microscopy, the cytoplasm of the clear cells was finely reticulated and vacuolated. Immunohistochemical and electron microscopy studies confirmed the endocrine nature of the tumour. Conclusions: The clear cell morphology was due to the accumulation of lipid in the cytoplasm.