• 1
    Friedmann P.S. 1989 Contact hypersensitivity. Curr Opin Immunol 1 690
  • 2
    Piguet P.F., Grau G.E., Hauser C., Vassalli P. 1991 Tumor necrosis factor is a critical mediator in haptene-induced irritant and contact hypersensitivity reactions. J Exp Med 173 673
  • 3
    Gautam S., Matriano J., Chikkala N., Edinger M., Tubbs R. 1991 L3T4 (CD4+) T cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants. Cell Immunol 135 27
  • 4
    Miller S.D. & Jenkins M.K. 1985 In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity. Cell Immunol 92 414
  • 5
    Issekutz T.B., Stolz J.M., Van Der Meide P. 1988 Lymphocyte recruitment in delayed-type hypersensitivity: the role of IFN-γ. J Immunol 140 2989
  • 6
    Skoglund C.A., Scheynius A., Holmdahl R., Van Der Meide P. 1986 Enhancement of DTH reaction and inhibition of the expression of class II transplantation antigens by in vivo treatment with antibodies against γ-interferon. Clin Exp Immunol 71 428
  • 7
    Thomson J.A., Troutt A.B., Kelso A. 1993 Contact sensitivity to oxazolone: involvement of both interferon-γ and interleukin-4 in oxazolone-specific Ig and T-cell response. Immunology 78 185
  • 8
    Gocinski B.L. & Tigelaar R.E. 1990 Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J Immunol 144 121
  • 9
    Ptak W., Szczpanik M., Rabamabhadran R., Askenase P.W. 1996 Immune or normal γδ T cells that assist αβ T cells in elicitation of contact sensitivity preferentially use Vγ5 and Vδ4 variable region gene segments. J Immunol 156 976
  • 10
    Dieli F., Asherson G.L., Sireci G. et al. 1997 γδ cells involved in contact sensitivity preferentially rearrange the Vγ3 region and require interleukin-7. Eur J Immunol 26 206
  • 11
    Dieli F., Ptak W., Sireci G. et al. 1998 Cross-talk between Vβ8+ and γδ+ T lymphocytes in contact sensitivity. Immunology 93 256
  • 12
    Xu H., Diiulio N.A., Fairchild R.L. 1996 T cell populations primed by haptene sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon-γ-producing (Tc1) effector CD8+ T cells and interleukin (IL) -4/IL-10-producing (Th2) negative regulatory CD4+ T cells. J Exp Med 183 1001
  • 13
    Steinbrink K., Sorg C., Mavher E. 1996 Low zone tolerance to contact allergens in mice: a functional role for CD8+ T helper type 2 cells. J Exp Med 183 759
  • 14
    Gautam S.C., Chikkala N.F., Hamilton T.A. 1992 Anti-inflammatory action of IL-4. J Immunol 148 1411
  • 15
    Berg D.J., Leach M.W., Kuhn R. et al. 1995 Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory response. J Exp Med 182 99
  • 16
    Weigmann B., Schwing J., Huber H. et al. 1997 Diminished contact hypersensitivity response in IL-4 deficient mice at a late phase of the elicitation reaction. Scand J Immunol 45 308
  • 17
    Dieli F., Asherson G.L., Colonna Romano G., Sireci G., Gervasi F., Salerno A. 1994 IL-4 is essential for the systemic transfer of delayed hypersensitivity by T cells. Role of γ/δ cells. J Immunol 152 2698
  • 18
    Salerno A., Dieli F., Sireci G., Bellavia A., Asherson G.L. 1995 Interleukin-4 is a critical cytokine in contact sensitivity. Immunology 84 404
  • 19
    Kuhn R., Rajewsky K., Muller W. 1991 Generation and analysis of interleukin-4 deficient mice. Science (Wash DC) 254 707
  • 20
    Kopf M., Le Gros G., Bachmann M., Lamers M., Bluethmann H., Kohler G. 1993 Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362 245
  • 21
    Asherson G.L. & Dieli F. 1992 Immune deviation in the mouse: transfer of selective depression of the contact sensitivity and interleukin-2 response, with retention of interferon gamma production requires CD8+ T cells. Immunology 76 427
  • 22
    Dieli F., Asherson G.L., Bonanno C.T., Sireci G., Salerno A. 1995 Major histocompatibility complex control of the class of the immune response to the haptene trinitrophenyl. Immunology 84 355
  • 23
    MacDonald H.R., Cerottini J.C., Ryser C.G. et al. 1980 Quantitation and cloning of cytolytic T lymphocytes and their precursors. Immunol Rev 51 93
  • 24
    Vadas M.A., Miller J.F.A.P., Gamble J., Whitelaw A. 1975 A radioisotopic method to measure delayed type hypersensitivity in the mouse. Int Arch Allergy Appl Immunol 49 670
  • 25
    Subramaniam M., Saffaripour S., Watson S.R., Mayadas T.N., Hynes R.D., Wagner D.D. 1995 Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-Selectin-deficient mice. J Exp Med 181 2277
  • 26
    Dieli F., Taniguchi M., Asherson G.L. et al. 1998 Development of haptene-induced IL-4-producing CD4+ T lymphocytes requires early IL-4 production by αβ T lymphocytes carrying invariant Vα14 TCR α chains. Int Immunol 10 244
  • 27
    Shornick L.P., De Togni P., Mariathasan S. et al. 1996 Mice deficient in IL-1β manifest impaired contact hypersensitivity to trinitrochlorobenzene. J Exp Med 183 1427
  • 28
    Chuang I., Chiang L., Chou C., Hsieh H. 1996 Different kinds of antigen-presenting cells exert different effects on T-helper cells development. Int Arch Allergy Immunol 111 366
  • 29
    Muller K., Jaunin F., Masouye I., Saurat J., Hauser C. 1990 Th2 cells mediate IL-4 dependent local tissue inflammation. J Immunol 150 5576
  • 30
    Werfel T., Hentschel M., Kapp A., Renz H. 1997 Dichotomy of blood- and skin-derived IL-4-producing allergen-specific T cells and restricted V beta repertoire in nickel-mediated contact dermatitis. J Immunol 158 2500
  • 31
    Salerno A. & Dieli F. 1998 Role of γδ cells in immune response in humans and mice. Crit Rev Immunol 18 327
  • 32
    Havran W.L. & Allison J.P. 1990 Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors. Nature 344 68
  • 33
    Barks J.L., McQuillan J.J., Iademarco M.F. 1997 TNF-α and IL-4 synergistically increase vascular cell adhesion molecule-1 expression in cultured vascular smooth muscle cells. J Immunol 159 4532
  • 34
    Bochner B.S., Klunk D.A., Sterbinsky S.A., Coffman R.L., Chleimer R.P. 1995 IL-13 selectively induces vascular cell adhesion molecule-1 expression in human endothelial cells. J Immunol 154 799
  • 35
    De Ruco L.P., Laat P.A., Matteucci C. et al. 1996 Expression of ICAM-1 and VCAM-1 in human malignant mesothelioma. J Pathol 179 266