Influence of resistant starch on the SCFA production and cell counts of butyrate-producing Eubacterium spp. in the human intestine
Article first published online: 18 JUN 2002
Journal of Applied Microbiology
Volume 93, Issue 1, pages 157–162, July 2002
How to Cite
Schwiertz, A. , Lehmann, U. , Jacobasch, G. and Blaut, M. (2002), Influence of resistant starch on the SCFA production and cell counts of butyrate-producing Eubacterium spp. in the human intestine. Journal of Applied Microbiology, 93: 157–162. doi: 10.1046/j.1365-2672.2002.01679.x
- Issue published online: 18 JUN 2002
- Article first published online: 18 JUN 2002
Aims: The genus Eubacterium, which is the second most common genus in the human intestine, includes several known butyrate producers. We hypothesized that Eubacterium species play a role in the intestinal butyrate production and are inducible by resistant starch.
Methods and Results: In a human pilot study species-specific and group-specific 16S rRNA-targeted, Cy3 (indocarbocyanine)-labelled oligonucleotide probes were used to quantify butyrogenic species of the genera Eubacterium, Clostridium and Ruminococcus. Following the intake of RS type III a significant increase in faecal butyrate but not in total SCFA was observed. However, increase in butyrate was not accompanied by a proliferation in the targeted bacteria.
Conclusions: The tested Eubacterium species have the capacity to produce butyrate but do not appear to play a major role for butyric acid production in the human intestine.
Significance and Impact of the Study: In view of the fact that the bacteria responsible for butyrate production are largely unknown, it is still difficult to devise a dietary intervention to stimulate butyrogenic bacteria in a targeted way.