The pathogenicity of strains of Salmonella paratyphi B and Salmonella java
Article first published online: 15 JAN 2003
Journal of Applied Microbiology
Volume 94, Issue 2, pages 340–348, February 2003
How to Cite
Chart, H. (2003), The pathogenicity of strains of Salmonella paratyphi B and Salmonella java. Journal of Applied Microbiology, 94: 340–348. doi: 10.1046/j.1365-2672.2003.01863.x
- Issue published online: 15 JAN 2003
- Article first published online: 15 JAN 2003
- 2002/345: received 3 September 2002, revised 18 November 2002 and accepted 28 November 2002
- enteric fever;
- pathogenic mechanisms;
- Salmonella java;
- Salmonella paratyphi B;
To relate the diseases caused by strains of Salmonella paratyphi B and S. java to pathogenic mechanisms expressed by these bacteria for the purpose of organism discrimination.
Methods and Results:
Epidemiological data relating to cases of disease caused by strains of S. paratyphi B and S. java, isolated over a 10-year period, were analysed with respect to patients’ symptoms, particularly those involving enteric fever. Strains of S. paratyphi B and S. java were also examined for a range of known pathogenic mechanisms. Infection with S. paratyphi B involved pyrexia in 12·5% of patients compared with 2·2% of patients infected with S. java. These organisms could not be differentiated based on the pathogenic properties examined.
Strains of S. paratyphi B appear not to be a major cause of enteric fever but primarily a cause of gastroenteritis, in common with S. java. Both organisms express similar pathogenic mechanisms, and strains of S. java are probably d-tartrate utilizing variants of S. paratyphi B.
Significance and Impact of the Study:
Strains of S. paratyphi B are very closely related organisms, primarily causing gastroenteritis. From this study it would appear that strains of S. paratyphi B are not a major cause of enteric fever.