Editor's note: since this article was accepted for publication, Johnson et al. (2002) have published a paper that develops in detail the notion of progressive subtle renal injury underlying the development of salt sensitivity in hypertension, several concepts of which are in accordance with the analysis and discussion presented herein.
Dietary salt and hypertension: a scientific issue or a matter of faith?
Article first published online: 28 JAN 2003
Journal of Evaluation in Clinical Practice
Volume 9, Issue 1, pages 1–22, February 2003
How to Cite
Robertson, J. I. S. (2003), Dietary salt and hypertension: a scientific issue or a matter of faith?. Journal of Evaluation in Clinical Practice, 9: 1–22. doi: 10.1046/j.1365-2753.2003.00359.x
A review of the long-term effects of dietary salt restriction in adult subjects has confirmed the modest antihypertensive effect. Systolic was lowered by a mean of 1.1 mmHg (95% CI 1.8–0.4); diastolic by a mean of 0.6 mmHg (1.5 to −0.3) at 13 to 60 months. Degree of reduction in sodium intake and change in blood pressure were not related (Hooper et al. 2002).
- Issue published online: 28 JAN 2003
- Article first published online: 28 JAN 2003
- body sodium content;
- cardiovascular disease
Many workers have an overly simplistic view of the relationship between salt intake and hypertension. This article attempts a critical evaluation of some of the evidence.