Tobacco use and cancer causation: association by tumour type
Article first published online: 19 SEP 2002
Journal of Internal Medicine
Volume 252, Issue 3, pages 206–224, September 2002
How to Cite
Kuper, H., Boffetta, P. and Adami, H.-O. (2002), Tobacco use and cancer causation: association by tumour type. Journal of Internal Medicine, 252: 206–224. doi: 10.1046/j.1365-2796.2002.01022.x
- Issue published online: 19 SEP 2002
- Article first published online: 19 SEP 2002
- Received 22 May 2002; accepted 31 May 2002.
Abstract. Kuper H, Boffetta P, Adami H-O (London School of Hygiene and Tropical Medicine, London, UK; Karolinska Institutet, Stockholm, Sweden; and International Agency for Research on Cancer, Lyon, France). Tobacco use and cancer causation: association by tumour type (Review). J Intern Med 2002; 252: 206–224.
In the second part of our review we describe the association between tobacco use and risk of specific cancer types. There is evidence for an established association of tobacco use with cancer of the lung and larynx, head and neck, bladder, oesophagus, pancreas, stomach and kidney. In contrast, endometrial cancer is less common in women who smoke cigarettes. There are some data suggesting that tobacco use increases the risk for myeloid leukaemia, squamous cell sinonasal cancer, liver cancer, cervical cancer, colorectal cancer after an extended latency, childhood cancers and cancer of the gall bladder, adrenal gland and small intestine. Other forms of cancer, including breast, ovarian and prostate cancer, are unlikely to be linked to tobacco use.