Sleep as restitution: an introduction
Article first published online: 16 JUN 2003
Journal of Internal Medicine
Volume 254, Issue 1, pages 6–12, July 2003
How to Cite
Åkerstedt, T. and Nilsson, P. M. (2003), Sleep as restitution: an introduction. Journal of Internal Medicine, 254: 6–12. doi: 10.1046/j.1365-2796.2003.01195.x
- Issue published online: 16 JUN 2003
- Article first published online: 16 JUN 2003
- Received 2 February 2003; revision received and accepted 1 April 2003.
- public health
Abstract. Åkerstedt T, Nilsson PM (Karolinska Institutet, Stockholm, University Hospital, Malmö, Sweden). Sleep as restitution: an introduction (Minisymposium). J Intern Med 2003; 254: 6–12.
This paper summarizes a symposium that has shown that sleep is a state of altered metabolism, and that disturbances and curtailments of sleep have far-reaching effects on endocrinology, immunology and metabolism, changes that may be linked to disease. As yet, the entire causal chain is weak but there are indications that, in particular, the risk of type 2 diabetes and cardiovascular disease may result from disturbed sleep. It is hypothesized that both insulin resistance and chronic low-grade inflammation may be involved.