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Retinal vein thrombosis associated with chronic hepatitis C: a case series and review of the literature


AbdulNadir Loyola University Medical Center, Department of Gastroenterology, Building 117, Room 8, 2160 S First Avenue, Maywood, IL 60153, USA.


The role of procoagulant autoantibodies in hepatitis C virus (HCV) infection is unclear. Three individuals with HCV infection and a unique genetic hypercoagulable state developed retinal vein thrombosis (RVT) in association with interferon-α (IFN-α) therapy. It is probable that a combination of active HCV infection in a genetically susceptible individual receiving IFN-α accounted for the observed RVT.