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References

  • 1
    Borg-von Zepelin, M., Beggah, S., Boggian, K., Sanglard, D., Monod, M. (1998) The expression of secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages. Mol Microbiol 28: 543554.
  • 2
    Borg-von Zepelin, M. & Rüchel, R. (1988) Expression of extracellular acid proteinase by proteolytic Candida spp. during experimental infection of oral mucosa. Infect Immun 56: 626631.
  • 3
    Colina, A.R., Aumont, F., Deslauriers, N., Belhumeur, P., De Repentigny, L. (1996) Evidence for degradation of gastrointestinal mucin by Candida albicans secretory aspartyl proteinase. Infect Immun 64: 45144519.
  • 4
    Cutler, J.E. (1991) Putative virulence factors of Candida albicans. Annu Rev Microbiol 45: 187218.
  • 5
    Dalton, A.J. (1955) A chrome-osmium fixative for electron microscopy. Anat Rec 121: 281.
  • 6
    De Bernardis, F., Cassone, A., Sturtevant, J., Calderone, R. (1995) Expression of Candida albicans SAP1 and SAP2 in experimental vaginitis. Infect Immun 63: 18871892.
  • 7
    De Bernardis, F., Boccanera, M., Adriani, D., Spreghini, E., Santoni, G., Cassone, A. (1997) Protective role of antimannan and anti-aspartyl proteinase antibodies in an experimental model of Candida albicans vaginitis in rats. Infect Immun 65: 33993405.
  • 8
    De Bernardis, F., Arancia, S., Morelli, L., Hube, B., Sanglard, D., Schäfer, W., Cassone, A. (1999) Evidence that members of secretory aspartyl proteinases gene family, in particular SAP2, are virulence factor for Candida vaginitis. J Infect Dis 179: 201208.
  • 9
    Dubois, N., Colina, A.R., Aumont, F., Belhumeur, P., De Repentigny, L. (1998) Overexpression of Candida albicans secretory aspartyl proteinase 2 and its expression in Saccharomyces cerevisiae do not augment virulence in mice. Microbiology 144: 22992310.
  • 10
    Fallon, K., Bausch, K., Noonan, B., Huguenel, E., Tamburini, P. (1997) Role of aspartic proteases in disseminated Candida albicans infection in mice. Infect Immun 65: 551556.
  • 11
    Farrell, S.M., Hawkins, D.F., Ryder, T.A. (1983) Scanning electron microscope study of Candida albicans invasion of cultured human cervical epithelial cells. Sabourodia 21: 251254.
  • 12
    Fonzi, W.A. & Irwin, M.Y. (1993) Isogenic strain construction and gene mapping in Candida albicans. Genetics 134: 717728.
  • 13
    Ghannoum, M. & Abu Elteen, K. (1986) Correlative relationship between proteinase production, adherence and pathogenicity of various strains of Candida albicans. J Med Vet Mycol 24: 407413.
  • 14
    Gillum, A.M., Tsay, E.Y.H., Kirsch, D.R. (1984) Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations. Mol Gen Genet 198: 179182.
  • 15
    Goldman, R.C., Frost, D.J., Capobianco, J.O., Kadam, S., Rasmussen, R.R., Abad-Zapatero, C. (1995) Antifungal drug targets: Candida secreted aspartyl protease and fungal wall beta-glucan synthesis. Infect Agents Dis 4: 228247.
  • 16
    Harder, J., Bartels, J., Christophers, E., Schröder, J.M. (1997) A peptide antibiotic from human skin. Nature 387: 61.
  • 17
    Hoegl, L., Ollert, M., Korting, H.C. (1996) The role of Candida albicans secreted aspartic proteinase in the development of candidoses. J Mol Med 74: 135142.
  • 18
    Homma, M., Chibana, H., Tanaka, K. (1991) Induction of extracellular proteinase in Candida albicans. J Gen Microbiol 139: 11871193.
  • 19
    Hube, B. (1996) Candida albicans secreted aspartyl proteinases. Curr Top Med Mycol 7: 5569.
  • 20
    Hube, B. (1998) Possible role of proteinases in Candida infections. Revista Iberoamericana Micologia 15: 6871.
  • 21
    Hube, B., Monod, M., Schofield, D.A., Brown, A.J.P., Gow, N.A.R. (1994) Expression of seven members of the gene family encoding secretory aspartyl proteinase in Candida albicans. Mol Microbiol 14: 8799.
  • 22
    Hube, B., Sanglard, D., Odds, F.C., Hess, D., Monod, M., Schäfer, W., et al (1997) Gene disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2 and SAP3 in Candida albicans attenuates virulence. Infect Immun 65: 35293538.
  • 23
    Ibrahim, A.S., Scott, G.F., Sanglard, D., Edwards, J.E., Hube, B. (1998) Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells. Infect Immun 66: 30033005.
  • 24
    Karnovsky, M.J. (1965) A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J Cell Biol 27: 137138.
  • 25
    Korting, H.C., Schaller, M., Eder, G., Hamm, G., Böhmer, U., Hube, B. (1999) Influence of the HIV-proteinase inhibitors saquinavir and indinavir on the in vitro activity of secreted aspartyl proteinases from Candida albicans isolates of HIV-infected patients. Antimicrob Agents Chemother 43: 20382042.
  • 26
    Kwon-Chung, K.J., Lehman, D., Good, C., Magee, P.T. (1985) Genetic evidence for role of extracellular proteinase in virulence of Candida albicans. Infect Immun 49: 571575.
  • 27
    MacDonald, F. & Odds, F.C. (1983) Virulence for mice of a proteinase-secreting strain of Candida albicans and a proteinase-deficient mutant. J Gen Microbiol 129: 431438.
  • 28
    Magee, B.B. (1994) Formation of Candida spheroplasts. In Molecular Biology of Pathogenic Fungi. Maresca, B., and Kobayashi, G.S. (eds). New York: Telos Press, pp. 113115.
  • 29
    Maneu, V., Cervera, A.M., Martinez, J.P., Gozalbo, D. (1996) Molecular cloning and characterization of a Candida albicans gene (EFB1) coding for the elongation factor EF-1β. FEMS Microbiol Lett 145: 157162.
  • 30
    Monod, M., Togni, G., Hube, B., Sanglard, D. (1994) Multiplicity of genes encoding secreted aspartic proteinases in Candida species. Mol Microbiol 13: 357368.
  • 31
    Monod, M., Hube, B., Hess, D., Sanglard, D. (1998) Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida Albicans. Microbiology 144: 27312737.
  • 32
    Morrow, B., Srikantha, T., Soll, D.R. (1992) Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans. Mol Cell Biol 12: 29973005.
  • 33
    Naglik, J., Newport, G., White, T.C., Fernandes-Naglik, L.L., Greenspan, J.S., Greenspan, D., et al (1999) In vivo analysis of secreted aspartyl proteinase expression in human oral candidiasis. Infect Immun 67: 24822490.
  • 34
    Odds, F.C. (1994) Candida species and virulence. Am Soc Microbiol News 60: 313318.
  • 35
    Ollert, M.W., Söhnchen, R., Korting, H.C., Ollert, U., Bräutigam, S., Bräutigam, W. (1993) Mechanisms of adherence of Candida albicans to cultured human epidermal keratinocytes. Infect Immun 61: 45604568.
  • 36
    Ray, T.L. & Payne, C.D. (1988) Scanning electron microscopy of epidermal adherence and cavitation in murine candidiasis: a role for Candida acid proteinase. Infect Immun 56: 19421949.
  • 37
    Reichart, P.A., Philipsen, H.P., Schmidt-Westhausen, A., Samaranayake, L.P. (1995) Pseudomembranous oral candidiasis in HIV infection: ultrastructural findings. J Oral Pathol Med 24: 276281.
  • 38
    Rüchel, R. (1992) Proteinase. In New Strategies in Fungal Disease. Bennett, J.E., Hay, R.J., and Peterson, P.K. (eds). Edinburgh: Churchill Livingstone, pp. 1731.
  • 39
    Rupniak, H.T., Rowlatt, C., Lane, E.B., Steele, J.G., Trejdosiewicz, L.K., Laskiewicz, B., et al (1985) Characteristics of four new human cell lines derived from squamous cell carcinomas of the head and neck. J Natl Cancer Inst 75: 621635.
  • 40
    Sanglard, D., Hube, B., Monod, M., Odds, F.C., Gow, N.A.R. (1997) A triple deletion in SAP4, SAP5 and SAP6 secretory aspartyl proteinase genes of Candida albicans causes attenuated virulence. Infect Immun 65: 35393546.
  • 41
    Schaller, M., Schäfer, W., Korting, H.C., Hube, B. (1998) Differential expression of secreted aspartyl proteinases in a model of human oral candidosis and in patient samples from the oral cavity. Mol Microbiol 29: 605615.
  • 42
    Schaller, M., Hube, B., Ollert, M.W., Schäfer, W., Borg-von Zepelin, M., Thoma-Greber, E., Korting, H.C. (1999) In vivo expression and localization of Candida albicans secreted aspartyl proteinases during oral candidiasis in HIV-infected patients. J Invest Dermatol 112: 383386.
  • 43
    Stringaro, A., Crateri, P., Pellegrini, G., Arancia;, G., Cassone, A., De Bernardis, F. (1997) Ultrastructural localization of the secretory aspartyl proteinase in Candida albicans cell wall in vitro and in experimentally infected rat vagina. Mycopathologia 137: 95105.
  • 44
    Watts, H.J., Cheah, F.S., Hube, B., Sanglard, D., Gow, N.A.R. (1998) Altered adherence in strains of Candida albicans harbouring null mutations in secreted aspartic proteinase genes. FEMS Microbiol Lett 159: 129135.
  • 45
    White, T.C. & Agabian, N. (1995) Candida albicans secreted aspartyl proteinases: isoenzyme pattern is determined by cell type, levels are determined by environmental factors. J Bacteriol 177: 52155221.